SCHEMBL502315

SCHEMBL502315

O=C1OCC(N(Cc2ccc(Cl)nc2)CC(F)F)=C1Cl

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CHRNA1 P02708 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
PRMT5 O14744 1/20 0.32
WDR77 Q9BQA1 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32
KDM4E B2RXH2 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
GRM2 Q14416 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30074797 0.89 CHRNA1 (0.32) CHRNA1CHRNB2CHRNA3CHRNA7CHRNA4
SCHEMBL502085 0.89 GRM2 (0.33) CHRNA1CHRNB2CHRNA3CHRNA7CHRNA4
SCHEMBL12863893 0.86 CHRNA1 (0.31) CHRNA1CHRNB2CHRNA3CHRNA7CHRNA4
SCHEMBL2892516 0.85 CHRNA1 (0.34) CHRNA1CHRNB2CHRNA3CHRNA7CHRNA4
SCHEMBL231409 0.80 MEN1 (0.33) CHRNA1CHRNB2CHRNA3CHRNA7CHRNA4
SCHEMBL29571833 0.80 MEN1 (0.33) CHRNA1CHRNB2CHRNA3CHRNA7CHRNA4
SCHEMBL123283 0.79 KDM1A (0.32) CHRNA1CHRNB2CHRNA3CHRNA7CHRNA4
SCHEMBL29394548 0.79 KDM1A (0.32) CHRNA1CHRNB2CHRNA3CHRNA7CHRNA4
SCHEMBL14243631 0.79 ALDH1A1 (0.33) CHRNA1CHRNB2CHRNA3CHRNA7CHRNA4
SCHEMBL29412273 0.79 ALDH1A1 (0.33) CHRNA1CHRNB2CHRNA3CHRNA7CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111970927-B Insecticidal mixture formulations comprising propylene carbonate 拜耳公司 2025-03-14 CN claimed
EP-4275493-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING GLYCOL ETHER SOLVENTS Bayer Aktiengesellschaft (DE) 2023-11-15 EP claimed
US-20230068010-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING GLYCOL ETHER SOLVENTS BAYER AKTIENGESELLSCHAFT (DE) 2023-03-02 US claimed
EP-4040962-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING GLYCOL ETHER SOLVENTS Bayer Aktiengesellschaft (DE) 2022-08-17 EP claimed
CN-114667062-A Pesticidal mixture formulations comprising glycol ether solvents 拜耳公司 2022-06-24 CN claimed
WO-2021069628-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING GLYCOL ETHER SOLVENTS BAYER AKTIENGESELLSCHAFT (DE) 2021-04-15 WO claimed
EP-3772943-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING PROPYLENE CARBONATE Bayer Aktiengesellschaft (DE) 2021-02-17 EP claimed
WO-2019197635-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING PROPYLENE CARBONATE BAYER AKTIENGESELLSCHAFT (DE) 2019-10-17 WO claimed
CN-111970927-B Insecticidal mixture formulations comprising propylene carbonate 拜耳公司 2025-03-14 CN disclosed
CN-114667062-B Insecticidal mixture formulations comprising glycol ether solvents 拜耳公司 2024-12-31 CN disclosed
EP-4275493-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING GLYCOL ETHER SOLVENTS Bayer Aktiengesellschaft (DE) 2023-11-15 EP disclosed
US-20230068010-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING GLYCOL ETHER SOLVENTS BAYER AKTIENGESELLSCHAFT (DE) 2023-03-02 US disclosed
EP-4040962-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING GLYCOL ETHER SOLVENTS Bayer Aktiengesellschaft (DE) 2022-08-17 EP disclosed
CN-114667062-A Pesticidal mixture formulations comprising glycol ether solvents 拜耳公司 2022-06-24 CN disclosed
EP-2044841-A1 Method for improving plant growth Bayer CropScience AG (DE) 2009-04-08 EP disclosed
EP-2004635-A1 SUBSTITUTED ENAMINOCARBONYL COMPOUNDS Bayer CropScience AG (DE) 2008-12-24 EP disclosed
WO-2008148483-A1 INSECTICIDE COMPOSITIONS HAVING AN IMPROVED EFFECT BAYER CROPSCIENCE AG (DE) 2008-12-11 WO disclosed
EP-2000027-A1 Insecticide compounds with improved effect Bayer CropScience AG (DE) 2008-12-10 EP disclosed
WO-2007115644-A1 SUBSTITUTED ENAMINOCARBONYL COMPOUNDS BAYER CROPSCIENCE AG (DE) 2007-10-18 WO disclosed
WO-2007115644-A1 SUBSTITUTED ENAMINOCARBONYL COMPOUNDS BAYER CROPSCIENCE AG (DE) 2007-10-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230068010-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING GLYCOL ETHER SOLVENTS SGMS2, SGMS1, CYP51A1 CHRNA1 4238/4885CHRNB2 3758/4885CHRNA3 3294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.