SCHEMBL502085

SCHEMBL502085

O=C1OCC(N(Cc2ccc(Cl)nc2)CC(F)F)=C1Br

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 1/20 0.33
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
PSEN1 P49768 1/20 0.30
PSEN2 P49810 1/20 0.30
APH1B Q8WW43 1/20 0.30
NCSTN Q92542 1/20 0.30
APH1A Q96BI3 1/20 0.30
PSENEN Q9NZ42 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
CHRNA1 P02708 1/20 0.30
CHRNB2 P17787 1/20 0.30
CHRNA3 P32297 1/20 0.30
CHRNA7 P36544 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL502315 0.89 CHRNA1 (0.33) GRM2MEN1KMT2AATML3MBTL1
SCHEMBL12863893 0.80 CHRNA1 (0.31) MEN1KMT2AATMCHRNA1CHRNB2
SCHEMBL231409 0.78 MEN1 (0.33) MEN1KMT2AATMPSEN1PSEN2
SCHEMBL29571833 0.78 MEN1 (0.33) MEN1KMT2AATMPSEN1PSEN2
SCHEMBL30074797 0.78 CHRNA1 (0.32) GRM2MEN1KMT2AATML3MBTL1
SCHEMBL123283 0.77 KDM1A (0.32) MEN1KMT2AATMPSEN1PSEN2
SCHEMBL14243631 0.77 ALDH1A1 (0.33) MEN1KMT2AATML3MBTL1KDM4E
SCHEMBL29412273 0.77 ALDH1A1 (0.33) MEN1KMT2AATML3MBTL1KDM4E
SCHEMBL29394548 0.77 KDM1A (0.32) MEN1KMT2AATMPSEN1PSEN2
SCHEMBL14949164 0.76 ALDH1A1 (0.33) GRM2MEN1KMT2AATMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4275493-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING GLYCOL ETHER SOLVENTS Bayer Aktiengesellschaft (DE) 2023-11-15 EP claimed
US-20230068010-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING GLYCOL ETHER SOLVENTS BAYER AKTIENGESELLSCHAFT (DE) 2023-03-02 US claimed
EP-4040962-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING GLYCOL ETHER SOLVENTS Bayer Aktiengesellschaft (DE) 2022-08-17 EP claimed
CN-114667062-A Pesticidal mixture formulations comprising glycol ether solvents 拜耳公司 2022-06-24 CN claimed
WO-2021069628-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING GLYCOL ETHER SOLVENTS BAYER AKTIENGESELLSCHAFT (DE) 2021-04-15 WO claimed
US-20100285965-A1 METHODS OF IMPROVING PLANT GROWTH BAYER CROPSCIENCE AG (DE) 2010-11-11 US claimed
EP-2090168-A1 Method for improving plant growth Bayer CropScience AG (DE) 2009-08-19 EP claimed
EP-2044841-A1 Method for improving plant growth Bayer CropScience AG (DE) 2009-04-08 EP claimed
CN-111970927-B Insecticidal mixture formulations comprising propylene carbonate 拜耳公司 2025-03-14 CN disclosed
CN-114667062-B Insecticidal mixture formulations comprising glycol ether solvents 拜耳公司 2024-12-31 CN disclosed
EP-4275493-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING GLYCOL ETHER SOLVENTS Bayer Aktiengesellschaft (DE) 2023-11-15 EP disclosed
US-20230068010-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING GLYCOL ETHER SOLVENTS BAYER AKTIENGESELLSCHAFT (DE) 2023-03-02 US disclosed
EP-4040962-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING GLYCOL ETHER SOLVENTS Bayer Aktiengesellschaft (DE) 2022-08-17 EP disclosed
CN-114667062-A Pesticidal mixture formulations comprising glycol ether solvents 拜耳公司 2022-06-24 CN disclosed
WO-2009046837-A2 METHODS OF IMPROVING PLANT GROWTH BAYER CROPSCIENCE AG (DE) 2009-04-16 WO disclosed
EP-2044841-A1 Method for improving plant growth Bayer CropScience AG (DE) 2009-04-08 EP disclosed
EP-2044841-A1 Method for improving plant growth Bayer CropScience AG (DE) 2009-04-08 EP disclosed
EP-2004635-A1 SUBSTITUTED ENAMINOCARBONYL COMPOUNDS Bayer CropScience AG (DE) 2008-12-24 EP disclosed
WO-2007115644-A1 SUBSTITUTED ENAMINOCARBONYL COMPOUNDS BAYER CROPSCIENCE AG (DE) 2007-10-18 WO disclosed
WO-2007115644-A1 SUBSTITUTED ENAMINOCARBONYL COMPOUNDS BAYER CROPSCIENCE AG (DE) 2007-10-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100285965-A1 METHODS OF IMPROVING PLANT GROWTH MYCBP, MYB, MRPL37 GRM2 842/4885MEN1 782/4885KMT2A 2317/4885
US-20230068010-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING GLYCOL ETHER SOLVENTS SGMS2, SGMS1, CYP51A1 GRM2 2296/4885MEN1 3305/4885KMT2A 3776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.