SCHEMBL5023158

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5016945	0.91	LMNA (0.52)	LMNAKDM4EKMT2AMAPTHPGD
	SCHEMBL5016964	0.91	LMNA (0.54)	LMNAKDM4EKMT2AMAPTHPGD
	SCHEMBL5022971	0.91	KDM4E (0.48)	LMNAKDM4EKMT2AMAPTHPGD
	SCHEMBL5016936	0.89	KDM4E (0.51)	LMNAKDM4EKMT2AMAPTHPGD
	SCHEMBL5022965	0.89	LMNA (0.53)	LMNAKDM4EKMT2AMAPTHPGD
	SCHEMBL5016995	0.89	MAPT (0.51)	LMNAKDM4EKMT2AMAPTHPGD
	SCHEMBL5023035	0.84	UBE2M (0.46)	LMNAKDM4EKMT2AMAPTHPGD
	SCHEMBL5016986	0.83	LMNA (0.46)	LMNAKDM4EKMT2AMAPTHPGD
	SCHEMBL5023546	0.81	KDM4E (0.51)	LMNAKDM4EKMT2AMAPTHPGD
	SCHEMBL5016974	0.81	KDM4E (0.51)	LMNAKDM4EKMT2AMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.