Known targets — ChEMBL curated mechanism
ACVR1ADORA1ADORA2AADORA2BADORA3ESR1ESR2FLT3GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSC1HRH1HTR7IDH1IDH2IRAK1JAK1JAK2JAK3MEN1OPRM1P2RX3PDE5ASCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASIGMAR1SLC6A2SYKTACR1TOP2ATYK2
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.88 |
| ▸ | HMGCR | P04035 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | SLC13A5 | Q86YT5 | 4/20 | 0.41 |
| ▸ | CPT2 | P23786 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL4191521 | 1.00 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL7197280 | 1.00 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL28736750 | 1.00 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL17941188 | 1.00 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL3408939 | 1.00 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL14574834 | 1.00 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL841663 | 1.00 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL18548768 | 1.00 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL23062790 | 0.97 | ALDH1A1 (0.94) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL20607531 | 0.97 | ALDH1A1 (0.94) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 334 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115889680-A | Curing agent for anti-moisture-absorption inorganic phosphate binder dry precoated sand and application thereof | 湖北工业大学 | 2023-04-04 | — | — | CN | claimed |
| WO-2021185464-A1 | A METHOD FOR OBTAINING A PREPARATION AND A PREPARATION COMPRISING ELECTROLYTES FOR UNGULATE ANIMALS, ESPECIALLY HORSES | ANWIPHARMA SP. Z O.O. (PL) | 2021-09-23 | — | — | WO | claimed |
| EP-4703451-A1 | COOLANT AND METHOD FOR PRODUCING COOLANT | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2026-03-04 | — | — | EP | disclosed |
| CN-118610487-B | Oxygen reduction catalyst with controllable hierarchical pore structure, and preparation method and application thereof | 佛山仙湖实验室 | 2025-04-08 | — | — | CN | disclosed |
| CN-115889680-B | Curing agent for moisture absorption resistant inorganic phosphate binder dry precoated sand and application thereof | 湖北工业大学 | 2025-04-01 | — | — | CN | disclosed |
| WO-2024225079-A1 | COOLANT AND METHOD FOR PRODUCING COOLANT | 三菱瓦斯化学株式会社 | 2024-10-31 | — | — | WO | disclosed |
| CN-118610487-A | Oxygen reduction catalyst with controllable hierarchical pore structure, and preparation method and application thereof | 佛山仙湖实验室 | 2024-09-06 | — | — | CN | disclosed |
| CN-118495526-A | Graphitized mesoporous carbon carrier with adjustable pore diameter and preparation method thereof | 青岛创启新能催化科技有限公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-117733167-B | Superfine metal nano-particles and preparation method thereof | 天津大学 | 2024-05-24 | — | — | CN | disclosed |
| EP-3763210-B1 | AGROCHEMICAL SPRAY SOLUTION | KURARAY CO (JP) | 2024-05-01 | — | — | EP | disclosed |
| US-11944093-B2 | Spreading agent for agrochemicals, and agrochemical spray solution | KURARAY CO., LTD. (JP) | 2024-04-02 | — | — | US | disclosed |
| EP-1253021-A2 | Inkjet recording sheet | FUJI PHOTO FILM CO., LTD. (JP) | 2002-10-30 | — | — | EP | disclosed |
| US-20020140796-A1 | Ink-jet recording material | SEIKO EPSON CORPORATION (JP) | 2002-10-03 | — | — | US | disclosed |
| EP-1219459-A2 | Ink-jet recording material | MITSUBISHI PAPER MILLS LIMITED (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-20020071018-A1 | Ink-jet recording material and use of the same | MITSUBISHI PAPER MILLS, LIMITED (JP) | 2002-06-13 | — | — | US | disclosed |
| US-20020045034-A1 | Ink-jet recording material | MITSUBISHI PAPER MILLS LIMITED (JP) | 2002-04-18 | — | — | US | disclosed |
| US-20020008753-A1 | Ink-jet recording material and ink-jet recording method | MITSUBISHI PAPER MILLS LIMITED (JP) | 2002-01-24 | — | — | US | disclosed |
| US-20020008752-A1 | Ink absorption layers comprising paper supports with high density polyethylene coatings and silica particles in polyvinyl alcohol binders having improved feeding and conveying in printers, gloss and wear resistance | MITSUBISHI PAPER MILLS LIMITED (JP) | 2002-01-24 | — | — | US | disclosed |
| EP-1138509-A2 | Ink-jet recording material and ink-jet recording method | MITSUBISHI PAPER MILLS LIMITED (JP) | 2001-10-04 | — | — | EP | disclosed |
| US-20010014381-A1 | Ink-jet recording material | MITSUBISHI PAPER MILLS LIMITED (JP) | 2001-08-16 | — | — | US | disclosed |