Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5023474 | 0.88 | F10 (0.76) | F10L3MBTL1MGLLLMNAHPGD | |
| SCHEMBL5022242 | 0.87 | F10 (0.77) | F10L3MBTL1MGLLLMNAHPGD | |
| SCHEMBL5022987 | 0.86 | F10 (0.76) | F10L3MBTL1MGLLLMNAHPGD | |
| SCHEMBL5022491 | 0.86 | F10 (0.76) | F10L3MBTL1MGLLLMNAHPGD | |
| SCHEMBL5026710 | 0.84 | F10 (1.00) | F10L3MBTL1MGLLLMNAHPGD | |
| SCHEMBL5023423 | 0.84 | F10 (0.73) | F10L3MBTL1MGLLLMNAHPGD | |
| SCHEMBL4445858 | 0.78 | F10 (0.69) | F10L3MBTL1LMNAALDH1A1POLB | |
| SCHEMBL15058756 | 0.76 | ALDH1A1 (0.60) | MGLLLMNAHPGDALDH1A1POLB | |
| SCHEMBL4443718 | 0.71 | F10 (0.94) | F10L3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL4445875 | 0.70 | F10 (1.00) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732918-B1 | NOVEL PYRROLIDINE-3,4-DICARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-11-12 | — | — | EP | disclosed |
| EP-1732918-A1 | NOVEL PYRROLIDINE-3,4-DICARBOXAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005092881-A1 | NOVEL PYRROLIDINE-3,4-DICARBOXAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-10-06 | — | — | WO | disclosed |