Sugi Predict

Sugi Predict / Compounds / SCHEMBL5023540

SCHEMBL5023540

SCHEMBL5023540

CCN(CC)S(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.73

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ HTT P42858 4/20 0.73
▸ LMNA P02545 4/20 0.73
▸ SMN1; SMN2 Q16637 3/20 0.73
▸ NPC1 O15118 1/20 0.66
▸ RAB9A P51151 1/20 0.66
▸ GLA P06280 1/20 0.61
▸ ALDH1A1 P00352 5/20 0.60
▸ CNR2 P34972 2/20 0.60
▸ MEN1 O00255 1/20 0.56
▸ KMT2A Q03164 1/20 0.56
▸ L3MBTL1 Q9Y468 1/20 0.56
▸ KDM1A O60341 1/20 0.54
▸ MAOA P21397 1/20 0.54
▸ MAOB P27338 1/20 0.54
▸ CNR1 P21554 1/20 0.54
▸ MAPT P10636 3/20 0.53
▸ MCOLN3 Q8TDD5 1/20 0.53
▸ TSHR P16473 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31649184 0.92 LMNA (0.62) HTTLMNASMN1; SMN2NPC1RAB9A
SCHEMBL7092691 0.87 CNR2 (0.57) HTTLMNASMN1; SMN2NPC1RAB9A
SCHEMBL7096588 0.87 CNR2 (0.60) HTTLMNASMN1; SMN2NPC1RAB9A
SCHEMBL7095853 0.87 CNR2 (0.60) HTTLMNASMN1; SMN2NPC1RAB9A
SCHEMBL12863040 0.87 CNR2 (0.74) CNR2CNR1
SCHEMBL23054305 0.85 LMNA (0.55) HTTLMNASMN1; SMN2NPC1RAB9A
SCHEMBL7097469 0.85 CNR2 (0.59) HTTLMNASMN1; SMN2NPC1RAB9A
SCHEMBL7201208 0.85 CNR2 (0.56) HTTLMNASMN1; SMN2NPC1RAB9A
SCHEMBL2469274 0.85 KDM4E (0.59) HTTLMNASMN1; SMN2NPC1RAB9A
SCHEMBL7091255 0.85 CNR2 (0.59) HTTLMNASMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4444275-A1 SYNERGISTIC TRANSPORT OF LIPOPHILIC AND HYDROPHILIC ACTIVE SUBSTANCES IN NANOPARTICLES Karlsruher Institut für Technologie (DE) 2024-10-16 — — EP claimed
CN-117659686-A Nylon composite material and preparation method and application thereof 江苏金发科技新材料有限公司 2024-03-08 — — CN claimed
CN-117402500-A Thermosetting composite modified asphalt suitable for emergency repair 朱吉鹏 2024-01-16 — — CN claimed
WO-2023104380-A1 SYNERGISTIC TRANSPORT OF LIPOPHILIC AND HYDROPHILIC ACTIVE SUBSTANCES IN NANOPARTICLES Karlsruher Institut für Technologie (DE) 2023-06-15 — — WO claimed
EP-4190312-A1 SYNERGISTIC TRANSPORT OF LIPOPHILIC AND HYDROPHILIC ACTIVE AGENTS INTO NANOPARTICLES Karlsruher Institut für Technologie (DE) 2023-06-07 — — EP claimed
WO-2022057210-A1 POLYAMIDE COMPOSITION HAVING NTC EFFECT AND PREPARATION METHOD THEREFOR 金发科技股份有限公司 2022-03-24 — — WO claimed
US-20040122021-A1 Enantiomers of 1-[(4-chlorophenyl)phenylmethyl)-4-[(4-methylphenyl)sulfonyl) piperazine COSSEMENT ERIC (BE) 2004-06-24 — — US claimed
US-20040122023-A1 Enantiomers of 1-[(4-chlorophenyl)phenylmethyl]-4-[(4-methylphenyl) sulfonyl] piperazine COSSEMENT ERIC (BE) 2004-06-24 — — US claimed
US-20030204089-A1 Enantiomers of 1-[(4-chlorophenyl) phenylmethyl]-4-[(4-methylphenyl) sulfonyl] piperazine COSSEMENT ERIC (BE) 2003-10-30 — — US claimed
EP-0617028-B1 Enantiomers of 1-[(4-chlorophenyl)phenylmethyl]-4-[(4-methylphenyl)sulfonyl] piperazine UCB SA (BE) 2000-06-14 — — EP claimed
EP-0617028-A1 Enantiomers of 1-(4-chlorophenyl)phenylmethyl)-4-(4-methylphenyl)sulfonyl piperazine U C B, S.A. (BE) 1994-09-28 — — EP claimed
JP-2147660-A — — None — — JP disclosed
CN-119838572-A Efficient heavy metal adsorption material and preparation method and application thereof 陕西科技大学 2025-04-18 — — CN disclosed
EP-4444275-A1 SYNERGISTIC TRANSPORT OF LIPOPHILIC AND HYDROPHILIC ACTIVE SUBSTANCES IN NANOPARTICLES Karlsruher Institut für Technologie (DE) 2024-10-16 — — EP disclosed
CN-117402500-A Thermosetting composite modified asphalt suitable for emergency repair 朱吉鹏 2024-01-16 — — CN disclosed
US-5106446-A Containing an aromatic polycarbonate and(or) polycaprolactone BAYER AKTIENGESELLSCHAFT (DE) 1992-04-21 — — US disclosed
EP-0475707-A2 Hot-melt ink composition SEIKO EPSON CORPORATION (JP) 1992-03-18 — — EP disclosed
JP-H02147660-A POLYURETHANE MIXTURE AND ITS USE AS ADHESIVE BAYER AG 1990-06-06 — — JP disclosed
EP-0335183-A2 Polyurethane blends and their use as adhesives BAYER AG (DE) 1989-10-04 — — EP disclosed
EP-0335182-A2 Use of Polyurethane-based compositions as adhesive BAYER AG (DE) 1989-10-04 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040122021-A1 Enantiomers of 1-[(4-chlorophenyl)phenylmethyl)-4-[(4-methylphenyl)sulfonyl) piperazine RPLP1, QDPR, RPLP2 HTT 828/4885LMNA 4169/4885SMN1; SMN2 682/4885
US-20030204089-A1 Enantiomers of 1-[(4-chlorophenyl) phenylmethyl]-4-[(4-methylphenyl) sulfonyl] piperazine RPLP1, QDPR, PRLHR HTT 886/4885LMNA 4245/4885SMN1; SMN2 738/4885
US-20040122023-A1 Enantiomers of 1-[(4-chlorophenyl)phenylmethyl]-4-[(4-methylphenyl) sulfonyl] piperazine RPLP1, QDPR, PRLHR HTT 886/4885LMNA 4245/4885SMN1; SMN2 738/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.