Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 9/20 | 0.81 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.81 |
| ▸ | PGR | P06401 | 4/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.81 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.81 |
| ▸ | HTR2B | P41595 | 1/20 | 0.81 |
| ▸ | LMNA | P02545 | 8/20 | 0.74 |
| ▸ | SERPINA6 | P08185 | 7/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.74 |
| ▸ | BLM | P54132 | 4/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.74 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.74 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 5/20 | 0.72 |
| ▸ | AR | P10275 | 3/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1899598 | 1.00 | SHBG (0.81) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL5023902 | 1.00 | SHBG (0.81) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL13575766 | 0.90 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL5021655 | 0.90 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL4442874 | 0.90 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL18657 | 0.90 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL18891626 | 0.90 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL6472960 | 0.90 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL13965283 | 0.90 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL13768123 | 0.90 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3129357-B1 | AFFINITY MEDICANT CONJUGATES | AF CHEMICALS LLC (US) | 2023-08-23 | — | — | EP | disclosed |
| EP-3860642-A1 | A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) | St. Anna Kinderkrebsforschung (AT) | 2021-08-11 | — | — | EP | disclosed |
| EP-3860643-A1 | A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) | St. Anna Kinderkrebsforschung (AT) | 2021-08-11 | — | — | EP | disclosed |
| US-20210077425-A1 | AFFINITY MEDICANT CONJUGATE | AF CHEMICALS, LLC (US) | 2021-03-18 | — | — | US | disclosed |
| WO-2020070289-A1 | A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) | ST. ANNA KINDERKREBSFORSCHUNG (AT) | 2020-04-09 | — | — | WO | disclosed |
| WO-2020070290-A1 | A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) | ST. ANNA KINDERKREBSFORSCHUNG (AT) | 2020-04-09 | — | — | WO | disclosed |
| US-9980926-B1 | Affinity medicant conjugate | AF CHEMICALS, LLC (US) | 2018-05-29 | — | — | US | disclosed |
| CN-101785775-B | Pharmaceutical application of 15- or 16- substituted testosterone analogues | PANTARHEI BIOSCIENCE BV | 2015-03-25 | — | — | CN | disclosed |
| CN-1694710-B | Pharmaceutical use of 15-or 16-substituted testosterone analogues | PANTARHEI BIOSCIENCE BV | 2012-09-05 | — | — | CN | disclosed |
| CN-101785775-A | Pharmaceutical application of 15- or 16- substituted testosterone analogues | PANTARHEI BIOSCIENCE BV | 2010-07-28 | — | — | CN | disclosed |
| EP-1427748-B1 | 17ALPHA-HYDROXY-14BETA-STEROIDS WITH HORMONAL EFFECT | ORGANON NV (NL) | 2008-05-14 | — | — | EP | disclosed |
| US-7169769-B2 | 17α-hydroxy-14β-steroids with hormonal effect | AKZO NOBEL N.V. (NL) | 2007-01-30 | — | — | US | disclosed |
| CN-1694710-A | Pharmaceutical use of 15-or 16-substituted testosterone analogues | PANTARHEI BIOSCIENCE BV (NL) | 2005-11-09 | — | — | CN | disclosed |
| US-20040259849-A1 | 17Alpha-hydroxy-14Beta-steroids with hormonal effect | MERCK SHARP & DOHME B.V. (NL) | 2004-12-23 | — | — | US | disclosed |
| EP-1427748-A1 | 17ALPHA-HYDROXY-14BETA-STEROIDS WITH HORMONAL EFFECT | Akzo Nobel N.V. (NL) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003022864-A1 | 17ALPHA-HYDROXY-14BETA-STEROIDS WITH HORMONAL EFFECT | AKZO NOBEL N.V. (NL) | 2003-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259849-A1 | 17Alpha-hydroxy-14Beta-steroids with hormonal effect | CYP17A1, HSD17B11, NR5A1 | SHBG 4/4885NR3C1 38/4885PGR 67/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.