Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Methyltestosterone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR known ✓ | P10275 | 3/20 | 0.72 |
| ▸ | SHBG | P04278 | 9/20 | 1.00 |
| ▸ | NR3C1 | P04150 | 5/20 | 1.00 |
| ▸ | PGR | P06401 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | ADRA1A | P35348 | 1/20 | 1.00 |
| ▸ | HTR2B | P41595 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 8/20 | 0.74 |
| ▸ | SERPINA6 | P08185 | 7/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.74 |
| ▸ | BLM | P54132 | 4/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.74 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.74 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 5/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyltestosterone SCHEMBL29416593 | 1.00 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL13575766 | 1.00 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL13965283 | 1.00 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL13768123 | 1.00 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL4442874 | 1.00 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL6472960 | 1.00 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL18891626 | 1.00 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL5021655 | 1.00 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL6152059 | 1.00 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL4575985 | 1.00 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 545311 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118400480-A | Method and system for virtual background group photo of user | 山东浪潮超高清智能科技有限公司 | 2024-07-26 | — | — | CN | claimed |
| CN-113778830-B | Automatic monitoring method for short video background music infringement behavior based on RPA technology | 长沙理工大学 | 2024-07-23 | — | — | CN | claimed |
| CN-113138932-B | Verification method, device and equipment for gesture recognition result of algorithm library | 北京字节跳动网络技术有限公司 | 2024-07-23 | — | — | CN | claimed |
| CN-118363648-A | Application development method and device, readable storage medium and electronic equipment | 北京宇信科技集团股份有限公司 | 2024-07-19 | — | — | CN | claimed |
| CN-118360527-A | Biomedical magnesium-based composite material with anti-tumor effect | 中国科学院金属研究所 | 2024-07-19 | — | — | CN | claimed |
| CN-221377815-U | Pen test electromagnetic ultrasonic thickness gauge with digital label recognition function | 哈尔滨长川超声仪器科技有限公司 | 2024-07-19 | — | — | CN | claimed |
| CN-118364469-A | Application secondary signature verification method, system, equipment and storage medium | 武汉天喻信息产业股份有限公司 | 2024-07-19 | — | — | CN | claimed |
| CN-118363856-A | Android software package system verification defect detection method based on constraint extraction | 电子科技大学 | 2024-07-19 | — | — | CN | claimed |
| CN-111814147-B | Android malicious software detection method based on model library | 武汉科技大学 | 2024-07-19 | — | — | CN | claimed |
| CN-118364454-A | Third party software development kit access control method, computer equipment and medium | 中兴通讯股份有限公司 | 2024-07-19 | — | — | CN | claimed |
| US-4622218-A | Testicular-specific drug delivery | UNIVERSITY OF FLORIDA (US) | 1986-11-11 | — | — | US | claimed |
| EP-0199768-A1 | A METHOD FOR THE PREVENTION OF OCULAR HYPERTENSION, TREATMENT OF GLAUCOMA AND TREATMENT OF OCULAR HYPERTENSION | KNEPPER, Paul A. (US) | 1986-11-05 | — | — | EP | claimed |
| WO-1986002554-A1 | A METHOD FOR THE PREVENTION OF OCULAR HYPERTENSION, TREATMENT OF GLAUCOMA AND TREATMENT OF OCULAR HYPERTENSION | KNEPPER PAUL A | 1986-05-09 | — | — | WO | claimed |
| US-4528271-A | Process for the intensification of microbiological conversions of steroids using cyclodextrin additives | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1985-07-09 | — | — | US | claimed |
| EP-0129893-A2 | Ground mixture | Takeda Chemical Industries, Ltd. (JP) | 1985-01-02 | — | — | EP | claimed |
| US-4323511-A | Steroid derivatives and their use in radioimmunoassays | E. R. SQUIBB & SONS, INC. (US) | 1982-04-06 | — | — | US | claimed |
| EP-0005558-B1 | STEROID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN RADIOIMMUNOASSAYS | E.R. Squibb & Sons, Inc. (US) | 1982-01-27 | — | — | EP | claimed |
| US-4230621-A | TRACERS, HYDROXYPHENYLGLUTARIC ACID DERIVATIVES | E. R. SQUIBB & SONS, INC. (US) | 1980-10-28 | — | — | US | claimed |
| EP-0010964-A1 | Ravidomycin, process of preparation and pharmaceutical compositions containing same | AYERST, MCKENNA AND HARRISON INC. (CA) | 1980-05-14 | — | — | EP | claimed |
| US-3962430-A | Sterilization of solid non-electrolyte medicinal agents employing sodium chloride | MERCK & CO., INC. (US) | 1976-06-08 | — | — | US | claimed |