SCHEMBL5023947

SCHEMBL5023947

CCc1cc(-c2cc(CC)c(O)c(CC)c2)cc(CC)c1O

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.55
GABRB2 P47870 1/20 0.55
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C9 P11712 1/20 0.45
CA1 P00915 3/20 0.41
CA2 P00918 3/20 0.41
HSD17B1 P14061 3/20 0.41
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
DHFR P00374 1/20 0.39
ESR1 P03372 2/20 0.37
ESR2 Q92731 2/20 0.37
PTPN2 P17706 1/20 0.36
PTPN1 P18031 1/20 0.36
PTPN6 P29350 1/20 0.36
ALDH1A1 P00352 1/20 0.35
SIRT1 Q96EB6 1/20 0.35
PTPN5 P54829 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1023740 0.86 PTPN1 (0.55) GABRA1GABRB2CYP1A2CYP3A4CYP2C9
SCHEMBL30250589 0.85 CA1 (0.59) GABRA1GABRB2CYP1A2CYP3A4CYP2C9
SCHEMBL31028130 0.85 CA1 (0.59) GABRA1GABRB2CYP1A2CYP3A4CYP2C9
SCHEMBL9749694 0.85 CA1 (0.59) GABRA1GABRB2CYP1A2CYP3A4CYP2C9
SCHEMBL18159476 0.84 PRKCE (0.47) GABRA1GABRB2CYP1A2CYP3A4CYP2C9
SCHEMBL15459274 0.84 PRKCE (0.47) GABRA1GABRB2CYP1A2CYP3A4CYP2C9
SCHEMBL15495702 0.84 PRKCE (0.47) GABRA1GABRB2CYP1A2CYP3A4CYP2C9
SCHEMBL13895963 0.84 TYR (0.46) GABRA1GABRB2CYP3A4ALOX15DHFR
SCHEMBL26249015 0.82 GABRA1 (0.40) GABRA1GABRB2CYP1A2CYP3A4CYP2C9
SCHEMBL69820 0.82 GABRA1 (0.55) GABRA1GABRB2CYP1A2CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024005194-A1 POLYPHENOL COMPOUND, FILM-FORMING COMPOSITION FOR LITHOGRAPHY, UNDERLAYER FILM FOR LITHOGRAPHY, AND METHOD FOR FORMING PATTERN 三菱瓦斯化学株式会社 2024-01-04 WO disclosed
US-9563121-B2 Actinic ray-sensitive or radiation-sensitive resin composition, and, actinic ray-sensitive or radiation-sensitive film and pattern forming method, each using the composition FUJIFILM CORPORATION (JP) 2017-02-07 US disclosed
US-9315435-B2 Method for producing hydroxyphenylcyclohexanol compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-04-19 US disclosed
US-9235116-B2 Actinic-ray- or radiation sensitive resin composition, actinic-ray- or radiation-sensitive film therefrom and method of forming pattern FUJIFILM CORPORATION (JP) 2016-01-12 US disclosed
US-20150141707-A1 METHOD FOR PRODUCING HYDROXYPHENYLCYCLOHEXANOL COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-05-21 US disclosed
EP-2842930-A1 METHOD FOR PRODUCING HYDROXYPHENYLCYCLOHEXANOL COMPOUND Sumitomo Chemical Company Limited (JP) 2015-03-04 EP disclosed
US-8906592-B2 Antireflective coating composition and process thereof AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (LU) 2014-12-09 US disclosed
US-20140342275-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, AND, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM AND PATTERN FORMING METHOD, EACH USING THE COMPOSITION FUJIFILM CORPORATION (JP) 2014-11-20 US disclosed
US-20140272692-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE COMPOSITION, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM USING THE SAME, PATTERN FORMING METHOD, MANUFACTURING METHOD OF ELECTRONIC DEVICE, ELECTRONIC DEVICE AND RESIN FUJIFILM CORPORATION (JP) 2014-09-18 US disclosed
US-8673538-B2 Actinic ray-sensitive or radiation-sensitive resin composition, and actinic ray-sensitive or radiation-sensitive film and pattern forming method using the composition FUJIFILM CORPORATION (JP) 2014-03-18 US disclosed
EP-0403022-A2 Encapsulating epoxy resin composition SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1990-12-19 EP disclosed
EP-0155517-B1 POLYESTER COMPOSITION AND PROCESS FOR PRODUCING SHAPED ARTICLES USING SAME KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-04-25 EP disclosed
US-H506-H AROMATIC POLYESTERS, HEAT RESISTANCE KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1988-08-02 US disclosed
US-4623710-A HEAT RESISTANCE, TRANSPARENCY, SURFACE RESISTANCE Kanegafuchi Kagaku Kogyo Kubushiki Kaisha (JP) 1986-11-18 US disclosed
EP-0196528-A2 Aromatic polyester film having silicone resin layer and liquid crystal display panel made therof KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1986-10-08 EP disclosed
EP-0093891-B1 HEAT-RESISTING AROMATIC POLYESTER AND PROCESS FOR PREPARING THE SAME KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1986-07-02 EP disclosed
EP-0171063-A2 Aromatic polyester films KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1986-02-12 EP disclosed
US-4552947-A Heat-resisting aromatic polyester and process for preparing the same KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1985-11-12 US disclosed
EP-0155517-A2 Polyester composition and process for producing shaped articles using same KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1985-09-25 EP disclosed
EP-0093891-A1 Heat-resisting aromatic polyester and process for preparing the same KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1983-11-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150141707-A1 METHOD FOR PRODUCING HYDROXYPHENYLCYCLOHEXANOL COMPOUND HSD11B2, CYP21A2, CYP11B2 GABRA1 1252/4885GABRB2 835/4885CYP1A2 17/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.