Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | CTSV | O60911 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | CTSC | P53634 | 1/20 | 0.31 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4054436 | 0.66 | GBA1 (0.34) | SLC6A2SLC6A4SLC6A3GBA1CHRM3 | |
| SCHEMBL15722779 | 0.65 | GBA1 (0.37) | HTR2CSLC6A2SLC6A4SLC6A3GBA1 | |
| SCHEMBL15749661 | 0.64 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3GBA1 | |
| Bromide SCHEMBL15709541 | 0.63 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3GBA1 | |
| SCHEMBL6440687 | 0.62 | HIF1A (0.47) | SLC6A2SLC6A4SLC6A3GBA1 | |
| SCHEMBL6688133 | 0.62 | SIGMAR1 (0.39) | HTR2ASLC6A2SLC6A4SLC6A3GBA1 | |
| SCHEMBL4282417 | 0.61 | EED (0.37) | HTR2CSLC6A2SLC6A4SLC6A3GBA1 | |
| SCHEMBL6926932 | 0.61 | SIGMAR1 (0.46) | HTR2CSLC6A2SLC6A4SLC6A3GBA1 | |
| SCHEMBL7833641 | 0.61 | CHRM3 (0.43) | GBA1CHRM3 | |
| Hydrochloric Acid SCHEMBL10944858 | 0.60 | SIGMAR1 (0.44) | SLC6A2SLC6A4SLC6A3GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1950199-A1 | Proline derivatives and use thereof as drugs | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-07-30 | — | — | EP | disclosed |