Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9711083 | 0.96 | LMNA (0.34) | LMNATP53HTTPDE2ATAAR1 | |
| Bromide SCHEMBL5088439 | 0.96 | LMNA (0.34) | LMNATP53HTTPDE2ATAAR1 | |
| Hydrochloric Acid SCHEMBL5092759 | 0.96 | LMNA (0.34) | LMNATP53HTTPDE2ATAAR1 | |
| SCHEMBL9064419 | 0.81 | GABRA1 (0.40) | LMNAHTTTAAR1CYP1A2CYP3A4 | |
| SCHEMBL22558408 | 0.80 | CYP1A2 (0.42) | LMNAHTTTAAR1CYP1A2CYP3A4 | |
| SCHEMBL166573 | 0.75 | GABRA1 (0.41) | TP53HTTTAAR1 | |
| SCHEMBL29619533 | 0.75 | GABRA1 (0.41) | TP53HTTTAAR1 | |
| SCHEMBL22589011 | 0.73 | LMNA (0.35) | LMNATP53HTTPDE2ATAAR1 | |
| Ammonia Solution, Strong SCHEMBL27539208 | 0.72 | GABRA1 (0.39) | TP53HTTTAAR1 | |
| SCHEMBL21343570 | 0.72 | GABRA1 (0.45) | LMNATP53HTTTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008036454-A1 | POLY (ARYLENE ETHER) COPOLYMER | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-03-27 | — | — | WO | disclosed |
| US-20080054234-A1 | Flame retardative resin composition | CHANG CHUN PLASTICS CO., LTD. (TW) | 2008-03-06 | — | — | US | disclosed |
| US-7084194-B2 | Halogen-free resin composition | CHANG CHUN PLASTICS CO., LTD. (TW) | 2006-08-01 | — | — | US | disclosed |
| US-6900269-B2 | Halogen-free resin composition | CHANG CHUN PLASTICS CO., LTD. (TW) | 2005-05-31 | — | — | US | disclosed |
| US-20040254305-A1 | Epoxy resin composition for photosemiconductor package | CHANG CHUN PLASTIC CO., LTD. (TW) | 2004-12-16 | — | — | US | disclosed |
| US-20040158023-A1 | Halogen-free resin composition | CHANG CHUN PLASTICS CO., LTD. (TW) | 2004-08-12 | — | — | US | disclosed |
| US-20040147640-A1 | Halogen-free resin composition | CHANG CHUN PLASTICS CO., LTD. (TW) | 2004-07-29 | — | — | US | disclosed |
| US-20040077821-A1 | Flame retarding resin composition | CHANG CHUN PLASTICS CO., LTD. (TW) | 2004-04-22 | — | — | US | disclosed |