Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 3/20 | 0.41 |
| ▸ | ARG2 | P78540 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 3/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.35 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.35 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | PEPD | P12955 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4450666 | 1.00 | ARG1 (0.41) | ARG1ARG2SLC7A5ANPEPRNPEP | |
| SCHEMBL13958625 | 0.84 | NR1H2 (0.38) | ARG1ARG2ANPEPRNPEPDNPEP | |
| SCHEMBL6580449 | 0.77 | NPFFR2 (0.46) | LARS1 | |
| SCHEMBL4450584 | 0.72 | CTSK (0.65) | CTSK | |
| SCHEMBL9928854 | 0.72 | MEN1 (0.37) | — | |
| SCHEMBL9928853 | 0.72 | MEN1 (0.37) | — | |
| SCHEMBL5096619 | 0.71 | CTSK (0.41) | ARG1ARG2SLC7A5LARS1MMP2 | |
| SCHEMBL5096613 | 0.71 | CTSK (0.41) | ARG1ARG2SLC7A5LARS1MMP2 | |
| SCHEMBL9928687 | 0.68 | CHRNB2 (0.31) | — | |
| SCHEMBL6127398 | 0.68 | CHRNB2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981596-A2 | NOVEL COMPOUNDS | SmithKline Beecham Corporation (US) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007082262-A2 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-19 | — | — | WO | disclosed |