SCHEMBL5027397

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2886416	0.90	IL2 (0.52)	IL2TP53TNFSTIM1ORAI1
	SCHEMBL5030848	0.85	IL2 (0.53)	IL2TP53TNFSTIM1ORAI1
	SCHEMBL15249596	0.82	IL2 (0.56)	IL2TP53TNFSTIM1ORAI1
	SCHEMBL5033848	0.79	IL2 (0.46)	IL2MAPTTP53TNFSTIM1
	SCHEMBL8233602	0.78	IL2 (0.48)	IL2TP53TNFSTIM1ORAI1
	SCHEMBL8263187	0.78	IL2 (0.64)	IL2MAPTTP53MEN1NPC1
	SCHEMBL15268308	0.73	IL2 (0.52)	IL2TP53TNFSTIM1ORAI1
	SCHEMBL1641679	0.73	RAB9A (0.65)	MAPTHTTMEN1NPC1RAB9A
	SCHEMBL988060	0.73	TP53 (0.45)	MAPTTP53HTTMEN1NPC1
	SCHEMBL12923855	0.73	TP53 (0.45)	MAPTTP53HTTMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.