SCHEMBL5027508

SCHEMBL5027508

C[Si](Cl)(Cl)OC1CCCCC1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.31
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
CA12 O43570 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5032364 0.84 ACHE (0.31) ACHECA1CA2CA12CA9
SCHEMBL5029872 0.84 ACHE (0.31) ACHECA1CA2CA12CA9
SCHEMBL5031088 0.80 CA1 (0.35) ACHECA1CA2CA12CA9
SCHEMBL8006501 0.78
SCHEMBL5577290 0.78
SCHEMBL5554325 0.78 CA1 (0.33) CA1CA2CA12CA9
SCHEMBL5031074 0.78 CA1 (0.33) CA1CA2CA12CA9
SCHEMBL301584 0.78 CA1 (0.33) ACHECA1CA2CA12CA9
SCHEMBL1049096 0.78 CA1 (0.33) ACHECA1CA2CA12CA9
SCHEMBL16569783 0.78 CA1 (0.33) ACHECA1CA2CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1999167-A2 ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR Novolen Technology Holdings, C.V. (NL) 2008-12-10 EP disclosed
WO-2007106348-A2 ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) 2007-09-20 WO disclosed
US-20070213204-A1 Ziegler-Natta catalyst with in situ-generated donor NOVOLEN TECHNOLOGY HOLDINGS C.V. 2007-09-13 US disclosed