Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | DRD4 | P21917 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5028143 | 1.00 | EPHX1 (0.69) | EPHX1HPGDDRD4RAB9ASMN1; SMN2 | |
| SCHEMBL20911011 | 0.89 | EPHX1 (0.84) | EPHX1HPGDDRD4RAB9ASMN1; SMN2 | |
| SCHEMBL23349229 | 0.88 | EPHX1 (0.73) | EPHX1HPGDDRD4RAB9ASMN1; SMN2 | |
| SCHEMBL24011289 | 0.86 | EPHX1 (0.71) | EPHX1HPGDDRD4RAB9ASMN1; SMN2 | |
| SCHEMBL5318930 | 0.86 | EPHX1 (0.69) | EPHX1HPGDDRD4RAB9ASMN1; SMN2 | |
| SCHEMBL2752603 | 0.83 | EPHX1 (0.97) | EPHX1HPGDDRD4RAB9ASMN1; SMN2 | |
| SCHEMBL6436349 | 0.82 | EPHX1 (1.00) | EPHX1HPGDDRD4RAB9ASMN1; SMN2 | |
| SCHEMBL8599433 | 0.79 | ALDH1A1 (0.69) | HPGDALDH1A1KMT2ATSHRHTR1A | |
| SCHEMBL6622416 | 0.79 | EPHX1 (0.73) | EPHX1HPGDDRD4RAB9ASMN1; SMN2 | |
| SCHEMBL8599432 | 0.79 | ALDH1A1 (0.69) | HPGDALDH1A1KMT2ATSHRHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221082-A1 | Ligands of Integrin Receptors | ABBOTT GMBH & CO. KG (DE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221082-A1 | Ligands of Integrin Receptors | ITGB3, ITGAV, ITGA2B | EPHX1 3454/4885HPGD 3104/4885DRD4 2971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.