Sugi Predict

Sugi Predict / Compounds / SCHEMBL502830

SCHEMBL502830

SCHEMBL502830

N[C@@H](C(=O)O)C(c1ccccc1)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 2/20 0.52
▸ CYP2D6 P10635 2/20 0.52
▸ SRC P12931 1/20 0.52
▸ LMNA P02545 2/20 0.50
▸ MAPK1 P28482 1/20 0.50
▸ SLC1A2 P43004 4/20 0.48
▸ SLC1A3 P43003 3/20 0.48
▸ SLC1A1 P43005 3/20 0.48
▸ F2 P00734 1/20 0.46
▸ GRM2 Q14416 1/20 0.46
▸ GRM3 Q14832 1/20 0.46
▸ MEN1 O00255 1/20 0.44
▸ CYP1A2 P05177 1/20 0.44
▸ CYP2C9 P11712 1/20 0.44
▸ CYP2C19 P33261 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ ALOX5 P09917 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL43670 1.00 DPP4 (0.52) DPP4CYP2D6SRCLMNAMAPK1
SCHEMBL43672 1.00 DPP4 (0.52) DPP4CYP2D6SRCLMNAMAPK1
SCHEMBL29360215 0.98 DPP4 (0.50) DPP4CYP2D6SRCLMNAMAPK1
Hydrochloric Acid SCHEMBL4799572 0.98 DPP4 (0.50) DPP4CYP2D6SRCLMNAMAPK1
Hydrochloric Acid SCHEMBL7582981 0.98 DPP4 (0.50) DPP4CYP2D6SRCLMNAMAPK1
Hydrochloric Acid SCHEMBL9445669 0.98 DPP4 (0.50) DPP4CYP2D6SRCLMNAMAPK1
Methane SCHEMBL29238636 0.98 DPP4 (0.50) DPP4CYP2D6SRCLMNAMAPK1
Carbamic Acid SCHEMBL29625257 0.96 CYP2D6 (0.48) DPP4CYP2D6SRCLMNAMAPK1
SCHEMBL7103757 0.88 LMNA (0.45) DPP4CYP2D6SRCLMNAMAPK1
Trifluoroacetic Acid SCHEMBL918979 0.88 SLC1A3 (0.44) DPP4CYP2D6SRCLMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 285 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4582436-A2 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 BicycleTX Limited (GB) 2025-07-09 — — EP claimed
US-20240391954-A1 MC4R AGONIST PEPTIDES THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-11-28 — — US claimed
CN-111741771-B Bicyclic peptide ligands specific for EPHA2 拜斯科技术开发有限公司 2024-08-06 — — CN claimed
EP-4392072-A1 MC4R AGONIST PEPTIDES The Regents Of The University Of Michigan (US) 2024-07-03 — — EP claimed
US-20240000957-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EphA2 BICYCLETX LIMITED (GB) 2024-01-04 — — US claimed
US-11696956-B2 Bicyclic peptide ligands specific for EphA2 BICYCLETX LIMITED (GB) 2023-07-11 — — US claimed
WO-2023028538-A1 MC4R AGONIST PEPTIDES THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2023-03-02 — — WO claimed
CN-115244067-A Synthetic antimicrobial peptides AJK生物制药有限责任公司 2022-10-25 — — CN claimed
US-20220289794-A1 SYNTHETIC ANTIMICROBIAL PEPTIDES AJK BIOPHARMACEUTICAL LLC (US) 2022-09-15 — — US claimed
EP-4021476-A1 SYNTHETIC ANTIMICROBIAL PEPTIDES AJK Biopharmaceutical, LLC (US) 2022-07-06 — — EP claimed
WO-2013026927-A1 POTENT LIGANDS OF THE GHRELIN RECEPTOR UNIVERSITÄT LEIPZIG (DE) 2013-02-28 — — WO claimed
EP-2562181-A1 Potent ligands of the ghrelin receptor Universität Leipzig (DE) 2013-02-27 — — EP claimed
US-20120277164-A1 GADD45BETA TARGETING AGENTS IMPERIAL INNOVATIONS LIMITED (GB) 2012-11-01 — — US claimed
EP-2491051-A2 GADD45BETA TARGETING AGENTS Imperial Innovations Limited (GB) 2012-08-29 — — EP claimed
WO-2011048390-A2 GADD45BETA TARGETING AGENTS IMPERIAL INNOVATIONS LIMITED (GB) 2011-04-28 — — WO claimed
EP-1932852-A1 Novel taxane related peptides and uses thereof Campiani, Giuseppe (IT) 2008-06-18 — — EP claimed
EP-1053249-A2 PEPTIDE INHIBITORS OF THE SERINE PROTEASE ACTIVITY ASSOCIATED TO THE NS3 PROTEIN OF HCV, RELEVANT USES AND PROCESS OF PRODUCTION Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. (IT) 2000-11-22 — — EP claimed
WO-1999038888-A2 PEPTIDE INHIBITORS OF THE SERINE PROTEASE ACTIVITY ASSOCIATED TO THE NS3 PROTEIN OF HCV, RELEVANT USES AND PROCESS OF PRODUCTION ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE (IT) 1999-08-05 — — WO claimed
WO-1993015042-A1 PROCESS FOR THE PREPARATION OF D(-) AND L(+)-3,3-DIPHENYLALANINE AND D(-) AND L(+)-SUBSTITUTED 3,3-DIPHENYLALANINES AND DERIVATIVES THEREOF WARNER-LAMBERT COMPANY (US) 1993-08-05 — — WO claimed
US-5198548-A Chemical intermediates for angiotensins WARNER-LAMBERT COMPANY (US) 1993-03-30 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240391954-A1 MC4R AGONIST PEPTIDES MC4R, MC3R, MC5R DPP4 676/4885CYP2D6 4670/4885SRC 3720/4885
US-11696956-B2 Bicyclic peptide ligands specific for EphA2 EPHA2, EPHB2, ERBB2 DPP4 1655/4885CYP2D6 3268/4885SRC 84/4885
US-20220289794-A1 SYNTHETIC ANTIMICROBIAL PEPTIDES VIP, HM13, NGLY1 DPP4 774/4885CYP2D6 4664/4885SRC 2745/4885
US-20240000957-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EphA2 EPHA2, EPHB2, ERBB2 DPP4 1655/4885CYP2D6 3268/4885SRC 84/4885
US-20120277164-A1 GADD45BETA TARGETING AGENTS DDB1, CCL2, DDIT3 DPP4 954/4885CYP2D6 3969/4885SRC 2860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.