SCHEMBL5028355

SCHEMBL5028355

c1ccc(-n2c3ccc(-c4cc(-n5c6ccc(-c7ccccc7-c7ccccn7)cc6c6ncccc65)c5oc6ccccc6c5c4)cc3c3ncccc32)cc1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.33
GRM5 P41594 1/20 0.32
PRKDC P78527 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5028305 0.93 GRM5 (0.31) GRM5
SCHEMBL10038536 0.93 ALOX5 (0.34) ALOX5PRKDC
SCHEMBL10038537 0.93 ALOX5 (0.35) ALOX5PRKDC
SCHEMBL12925664 0.92 GRM5 (0.31) GRM5
SCHEMBL1610450 0.91 GRM5 (0.33) ALOX5GRM5PRKDC
SCHEMBL5028371 0.90 KDM4E (0.35) ALOX5
SCHEMBL5028379 0.87 KDM4E (0.32) GRM5
SCHEMBL10038545 0.86 MAPK14 (0.34) ALOX5GRM5PRKDC
SCHEMBL5028391 0.86 KDM4E (0.33) GRM5PRKDC
SCHEMBL5028299 0.85 MAPK14 (0.32) ALOX5GRM5PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9040975-B2 Organic electroluminescence element, illumination device, and display device Konica Minolta, Inc. (JP) 2015-05-26 US disclosed
US-9040975-B2 Organic electroluminescence element, illumination device, and display device Konica Minolta, Inc. (JP) 2015-05-26 US disclosed
EP-2453496-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, NOVEL COMPOUND, LIGHTING DEVICE AND DISPLAY DEVICE Konica Minolta Holdings, Inc. (JP) 2012-05-16 EP disclosed
US-20110006670-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2011-01-13 US disclosed
US-20110006670-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2011-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110006670-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME AOC2, AOC3, CDYL ALOX5 855/4885GRM5 2093/4885PRKDC 3081/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.