Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 4/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 11/20 | 0.36 |
| ▸ | ITGAV | P06756 | 11/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 9/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 9/20 | 0.36 |
| ▸ | ITGB5 | P18084 | 9/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5028389 | 0.86 | ITGB3 (0.41) | ITGB3ITGAVITGB5ITGA2B | |
| SCHEMBL5024033 | 0.86 | GRIN2B (0.42) | GRIN2BNPY5RITGB3ITGAVITGB1 | |
| SCHEMBL5025680 | 0.81 | ITGB3 (0.47) | ITGB3ITGAV | |
| SCHEMBL5879510 | 0.78 | GRIN2B (0.41) | GRIN2BNPY5RITGB3ITGAVITGB1 | |
| SCHEMBL6439335 | 0.76 | GRIN2B (0.41) | GRIN2BNPY5RITGB3ITGAVITGB1 | |
| SCHEMBL6424125 | 0.73 | ITGB3 (0.54) | ITGB3ITGAV | |
| SCHEMBL5024072 | 0.71 | ITGB3 (0.56) | ITGB3ITGAV | |
| SCHEMBL5025678 | 0.68 | ITGB3 (0.47) | ITGB3ITGAV | |
| SCHEMBL6441098 | 0.66 | ITGB3 (0.38) | GRIN2BITGB3ITGAVITGB5ITGA2B | |
| SCHEMBL5026359 | 0.66 | MME (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221082-A1 | Ligands of Integrin Receptors | ABBOTT GMBH & CO. KG (DE) | 2008-09-11 | — | — | US | disclosed |
| EP-1286673-B1 | LIGANDS OF INTEGRIN RECEPTORS | BASF AG (DE) | 2005-05-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221082-A1 | Ligands of Integrin Receptors | ITGB3, ITGAV, ITGA2B | GRIN2B 1632/4885NPY5R 1289/4885ITGB3 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.