Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.38 |
| ▸ | ITGAV | P06756 | 11/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SLC40A1 | Q9NP59 | 7/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5024072 | 0.85 | ITGB3 (0.56) | ITGB3ITGAVHTR2BSLC40A1 | |
| SCHEMBL6426185 | 0.82 | ITGB3 (0.51) | ITGB3ITGAVSLC40A1 | |
| SCHEMBL5028389 | 0.82 | ITGB3 (0.41) | ITGB3ITGAVHTR2BSLC40A1ITGA2B | |
| SCHEMBL6439157 | 0.73 | ITGB3 (0.40) | ITGB3ITGAV | |
| SCHEMBL6439941 | 0.73 | ITGB3 (0.49) | ITGB3ITGAV | |
| SCHEMBL6439335 | 0.70 | GRIN2B (0.41) | ITGB3ITGAVITGA2BITGB5GRIN2B | |
| SCHEMBL5897564 | 0.70 | HTR2B (0.53) | ITGB3ITGAVHTR2BITGA2BITGB5 | |
| SCHEMBL6440635 | 0.70 | ITGB3 (0.55) | ITGB3ITGAV | |
| SCHEMBL6426183 | 0.69 | ITGB3 (0.51) | ITGB3ITGAVSLC40A1 | |
| SCHEMBL6446498 | 0.69 | ITGB3 (0.46) | ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286673-B8 | LIGANDS OF INTEGRIN RECEPTORS | ABBOTT GMBH & CO KG (DE) | 2005-07-20 | — | — | EP | disclosed |
| EP-1286673-A2 | LIGANDS OF INTEGRIN RECEPTORS | Basf Aktiengesellschaft (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001093840-A2 | LIGANDS OF INTEGRIN RECEPTORS | BASF AG (DE) | 2001-12-13 | — | — | WO | disclosed |