Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL5546505 | 0.98 | KDM4A (0.32) | KDM4AKDM4CLMNATDP1MEN1 | |
| Sulfuric Acid SCHEMBL1833252 | 0.92 | CA5A (0.35) | LMNATDP1ALDH1A1CA5ACA5B | |
| Sulfuric Acid SCHEMBL1343065 | 0.92 | CA5A (0.35) | LMNATDP1ALDH1A1CA5ACA5B | |
| Sulfuric Acid SCHEMBL28950519 | 0.90 | CA5A (0.33) | LMNATDP1ALDH1A1CA5ACA5B | |
| Sulfuric Acid SCHEMBL28950522 | 0.90 | CA5A (0.33) | LMNATDP1ALDH1A1CA5ACA5B | |
| Bicarbonate SCHEMBL1830889 | 0.89 | MEN1 (0.36) | KDM4AKDM4CMEN1USP2ALDH1A1 | |
| Bicarbonate SCHEMBL600163 | 0.89 | — | — | |
| SCHEMBL1833887 | 0.87 | LMNA (0.38) | LMNATDP1 | |
| SCHEMBL11143687 | 0.82 | EPHX1 (0.36) | LMNATDP1 | |
| Oxalic Acid SCHEMBL1837735 | 0.81 | KDM4E (0.39) | KDM4AKDM4CLMNATDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948589-A1 | IONIC LIQUIDS | Bioniqs Limited (GB) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007036712-A1 | IONIC LIQUIDS | BIONIQS LIMITED (GB) | 2007-04-05 | — | — | WO | disclosed |