SCHEMBL5028631

SCHEMBL5028631

Oc1ccc(-c2ccc(O)c(Br)c2)cc1Br

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 4/20 0.62
APP P05067 2/20 0.55
ALOX5 P09917 3/20 0.46
ESR1 P03372 3/20 0.46
ESR2 Q92731 3/20 0.46
ALOX12 P18054 2/20 0.43
CRHBP P24387 1/20 0.42
CRHR2 Q13324 1/20 0.42
SNCA P37840 2/20 0.42
HSD17B10 Q99714 2/20 0.42
CYP3A4 P08684 1/20 0.42
PTPN1 P18031 1/20 0.41
QDPR P09417 1/20 0.41
CSNK2A2 P19784 1/20 0.40
CSNK2B P67870 1/20 0.40
CSNK2A1 P68400 1/20 0.40
IDO1 P14902 1/20 0.40
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
USP2 O75604 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30268624 1.00 ALOX15 (0.62) ALOX15APPALOX5ESR1ESR2
SCHEMBL9622875 0.90 ALOX5 (0.62) ALOX15APPALOX5ESR1ESR2
SCHEMBL3339161 0.90 ALOX15 (0.65) ALOX15APPALOX5ESR1ESR2
SCHEMBL30144854 0.88 ALOX5 (0.64) ALOX15APPALOX5ESR1ESR2
SCHEMBL1371332 0.88 ALOX5 (0.64) ALOX15APPALOX5ESR1ESR2
SCHEMBL15674473 0.86 ALOX15 (0.48) ALOX15APPALOX5ESR1ESR2
SCHEMBL15674635 0.86 ALOX5 (0.65) ALOX15APPALOX5ESR1ESR2
SCHEMBL6268020 0.84 ALOX15 (0.46) ALOX15APPESR1ESR2HSD17B10
SCHEMBL3973927 0.81 HRH3 (0.54) ALOX15APPSNCAHSD17B10CYP3A4
SCHEMBL3688519 0.81 KDM4E (0.62) HSD17B10KDM4ELMNAGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119140066-A Modified activated carbon adsorbent and preparation method thereof 宁夏尼西活性炭有限公司 2024-12-17 CN claimed
CN-117343276-B Preparation method of flame-retardant double-component polyurethane pouring sealant 烟台万华聚氨酯合成材料有限公司 2024-02-06 CN claimed
US-5235025-A Cross-linkable thermotropic liquid crystalline aromatic polyester HIMONT ITALIA S.R.L. (IT) 1993-08-10 US claimed
EP-0383177-A2 Cross-linkable thermotropic liquid crystalline aromatic polyesters HIMONT ITALIA S.r.l. (IT) 1990-08-22 EP claimed
US-4923947-A Thermotropic liquid crystalline aromatic polyesters of disubstituted 4,4'-dihydroxydiphenylene MONTEDISON S.P.A. (IT) 1990-05-08 US claimed
EP-0324608-A2 Thermotropic liquid crystalline aromatic polyesters Montedison S.p.A. (IT) 1989-07-19 EP claimed
US-20250109219-A1 FLUOROELASTOMER CROSSLINKABLE COMPOSITION AND ARTICLE DAIKIN INDUSTRIES, LTD. (JP) 2025-04-03 US disclosed
EP-4506414-A1 COMPOSITION FOR FLUORINE RUBBER CROSSLINKING AND MOLDED ARTICLE DAIKIN INDUSTRIES, LTD. (JP) 2025-02-12 EP disclosed
CN-119140066-A Modified activated carbon adsorbent and preparation method thereof 宁夏尼西活性炭有限公司 2024-12-17 CN disclosed
CN-118325562-A Flame-retardant bi-component polyurethane pouring sealant and preparation method thereof 广东德聚技术股份有限公司 2024-07-12 CN disclosed
CN-117343276-B Preparation method of flame-retardant double-component polyurethane pouring sealant 烟台万华聚氨酯合成材料有限公司 2024-02-06 CN disclosed
WO-2023195469-A1 COMPOSITION FOR FLUORINE RUBBER CROSSLINKING AND MOLDED ARTICLE ダイキン工業株式会社 2023-10-12 WO disclosed
WO-2022136231-A1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2022-06-30 WO disclosed
US-4895755-A ENCAPSULATION OF ELECTRONIC COMPONENTS THE DOW CHEMICAL COMPANY (US) 1990-01-23 US disclosed
EP-0324608-A2 Thermotropic liquid crystalline aromatic polyesters Montedison S.p.A. (IT) 1989-07-19 EP disclosed
US-4783363-A ELECTRICAL LAMINATES THE DOW CHEMICAL COMPANY (US) 1988-11-08 US disclosed
US-4746721-A ENGINEERING PLASTICS KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1988-05-24 US disclosed
WO-1988002012-A1 HALOGENATED EPOXY RESINS AND ADVANCED RESINS PREPARED THEREFROM THE DOW CHEMICAL COMPANY (US) 1988-03-24 WO disclosed
US-4727119-A HALOGEN ATOM IN META POSITION WITH RESPECT TO GLYCIDYL ETHER ENCAPSULATION ELECTRICAL COMPONENTS THE DOW CHEMICAL COMPANY (US) 1988-02-23 US disclosed
EP-0212944-A2 Melt-processable aromatic copolyester Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1987-03-04 EP disclosed