SCHEMBL650000

SCHEMBL650000

c1ccc(-c2cccc(-c3ccccn3)c2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.54
LMNA P02545 5/20 0.54
CCR1 P32246 2/20 0.54
CCR5 P51681 2/20 0.54
CCR8 P51685 2/20 0.54
CYP1A2 P05177 1/20 0.54
POLB P06746 1/20 0.54
METAP1 P53582 1/20 0.54
BLM P54132 1/20 0.54
HIF1A Q16665 1/20 0.54
DOHH Q9BU89 1/20 0.54
P4HTM Q9NXG6 1/20 0.54
CYP2A6 P11509 1/20 0.53
TP53 P04637 5/20 0.52
SMN1; SMN2 Q16637 4/20 0.52
L3MBTL1 Q9Y468 3/20 0.52
ALOX15 P16050 2/20 0.52
HTT P42858 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
ALPL P05186 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30088399 1.00 KDM4E (0.54) KDM4ELMNACCR1CCR5CCR8
SCHEMBL13799178 1.00 KDM4E (0.54) KDM4ELMNACCR1CCR5CCR8
SCHEMBL26499031 1.00 KDM4E (0.54) KDM4ELMNACCR1CCR5CCR8
SCHEMBL24492797 0.98 KDM4E (0.52) KDM4ELMNACCR1CCR5CCR8
SCHEMBL26499340 0.98 KDM4E (0.52) KDM4ELMNACCR1CCR5CCR8
SCHEMBL27842924 0.98 KDM4E (0.52) KDM4ELMNACCR1CCR5CCR8
SCHEMBL2188788 0.98 KDM4E (0.52) KDM4ELMNACCR1CCR5CCR8
SCHEMBL14425486 0.98 KDM4E (0.52) KDM4ELMNACCR1CCR5CCR8
SCHEMBL21334236 0.98 KDM4E (0.52) KDM4ELMNACCR1CCR5CCR8
SCHEMBL26498677 0.98 KDM4E (0.52) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12162899-B2 Photochromic germole-fused diarylethenes and production thereof THE UNIVERSITY OF HONG KONG (CN) 2024-12-10 US claimed
CN-116425791-A Photochromic germanium-doped cyclopentadiene condensed diaryl ethylene and preparation thereof 香港大学 2023-07-14 CN claimed
US-20230167139-A1 PHOTOCHROMIC GERMOLE-FUSED DIARYLETHENES AND PRODUCTION THEREOF THE UNIVERSITY OF HONG KONG (CN) 2023-06-01 US claimed
WO-1992001766-A1 FERROELECTRIC LIQUID CRYSTAL COMPOSITIONS CONTAINING HALOGENATED CORES AND CHIRAL HALOALKOXY TAIL UNITS DISPLAYTECH, INC. (US) 1992-02-06 WO claimed
US-12162899-B2 Photochromic germole-fused diarylethenes and production thereof THE UNIVERSITY OF HONG KONG (CN) 2024-12-10 US disclosed
US-12127470-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-10-22 US disclosed
US-12022727-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-06-25 US disclosed
CN-117460288-A Organic electroluminescent device, display panel and display device 京东方科技集团股份有限公司 2024-01-26 CN disclosed
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-26 US disclosed
US-20230345828-A1 COMPOUND, COMPOSITION AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-26 US disclosed
US-20230322691-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CANON KABUSHIKI KAISHA (JP) 2023-10-12 US disclosed
US-20230320188-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-05 US disclosed
WO-2004095601-A2 ORGANIC LIGHT EMITTING DEVICES HAVING REDUCED PIXEL SHRINKAGE UNIVERSAL DISPLAY CORPORATION (US) 2004-11-04 WO disclosed
US-20040214038-A1 Organic light emitting devices having reduced pixel shrinkage UNIVERSAL DISPLAY CORPORATION 2004-10-28 US disclosed
WO-2004044089-A1 ORGANOMETALLIC COMPOUNDS FOR USE IN ELECTROLUMINESCENT DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2004-05-27 WO disclosed
US-20040086743-A1 Organometallic compounds for use in electroluminescent devices UNIVERSAL DISPLAY CORPORATION 2004-05-06 US disclosed
US-20030068536-A1 Such as bis(4-biphenyl-4-yl)pyridine-C3-N3)(acetylacetonato-) iridium (III); brightness; phosphorescence; graphic arts CANON KABUSHIKI KAISHA (JP) 2003-04-10 US disclosed
EP-1239526-A2 Metal coordination compound, luminescene device and display apparatus CANON KABUSHIKI KAISHA (JP) 2002-09-11 EP disclosed
CN-1187814-A (hetero) aryloxy-, -thio-and-aminocrotonates, preparation and use thereof BASF AG (DE) 1998-07-15 CN disclosed
CN-1145619-A Substituted pyridine leukotriene B4 antagonists HOFFMANN LA ROCHE (CH) 1997-03-19 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230345828-A1 COMPOUND, COMPOSITION AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OCIAD2, OXER1, OR51E2 KDM4E 3503/4885LMNA 4806/4885CCR1 468/4885
US-12162899-B2 Photochromic germole-fused diarylethenes and production thereof AGL, GMNN, GAK KDM4E 2397/4885LMNA 1450/4885CCR1 3987/4885
US-20230320188-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, MLX KDM4E 1550/4885LMNA 485/4885CCR1 802/4885
US-12127470-B2 Organic electroluminescent materials and devices SOD1, CLTB, L1CAM KDM4E 3163/4885LMNA 87/4885CCR1 1965/4885
US-20230322691-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CCNT1, CCNE2, SCO2 KDM4E 3380/4885LMNA 701/4885CCR1 530/4885
US-12022727-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 KDM4E 4507/4885LMNA 1193/4885CCR1 2519/4885
US-20230167139-A1 PHOTOCHROMIC GERMOLE-FUSED DIARYLETHENES AND PRODUCTION THEREOF AGL, GMNN, GAK KDM4E 2397/4885LMNA 1450/4885CCR1 3987/4885
US-20040214038-A1 Organic light emitting devices having reduced pixel shrinkage OCIAD1, MAP1LC3B, OCIAD2 KDM4E 1582/4885LMNA 4627/4885CCR1 4038/4885
US-20030068536-A1 Such as bis(4-biphenyl-4-yl)pyridine-C3-N3)(acetylacetonato-) iridium (III); brightness; phosphorescence; graphic arts CYC1, CYCS, CCNA1 KDM4E 4117/4885LMNA 2201/4885CCR1 792/4885
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OPRD1, L1CAM, OPRM1 KDM4E 4161/4885LMNA 338/4885CCR1 1427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.