SCHEMBL7052588

SCHEMBL7052588

NC(=O)c1c(I)c(NC(=O)CCl)c(I)c(C(=O)NCC(O)CO)c1I

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.53
CYP2C19 P33261 1/20 0.47
HIF1A Q16665 1/20 0.47
EGFR P00533 1/20 0.33
SRC P12931 1/20 0.33
MAP2K1 Q02750 7/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
TEAD1 P28347 1/20 0.32
YAP1 P46937 1/20 0.32
TEAD4 Q15561 1/20 0.32
TEAD2 Q15562 1/20 0.32
MAP2K2 P36507 2/20 0.31
PRKCZ Q05513 1/20 0.31
IARS2 Q9NSE4 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5028753 0.95 LMNA (0.57) LMNACYP2C19HIF1AEGFRSRC
SCHEMBL3718498 0.91 LMNA (0.56) LMNACYP2C19HIF1AEGFRSRC
SCHEMBL7995861 0.90 LMNA (0.55) LMNACYP2C19HIF1AEGFRSRC
SCHEMBL9009053 0.85 LMNA (0.58) LMNACYP2C19HIF1AEGFRSRC
SCHEMBL14958965 0.85 LMNA (0.54) LMNACYP2C19HIF1AEGFRSRC
SCHEMBL13041034 0.85 LMNA (0.54) LMNACYP2C19HIF1AEGFRSRC
SCHEMBL11292903 0.85 LMNA (0.59) LMNACYP2C19HIF1AEGFRSRC
SCHEMBL8905699 0.85 LMNA (0.55) LMNACYP2C19HIF1AEGFRSRC
SCHEMBL23188236 0.84 LMNA (0.53) LMNACYP2C19HIF1AEGFRSRC
SCHEMBL5030922 0.84 LMNA (0.60) LMNACYP2C19HIF1AEGFRSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116421744-A Absorbable medical hydrogel and preparation method thereof 杭州融华再生医学科技有限公司 2023-07-14 CN claimed
EP-0839056-A4 PROCESS FOR PRODUCING IOVERSOL MALLINCKRODT MEDICAL INC (US) 2000-09-13 EP claimed
EP-0886634-A4 PROCESS FOR PRODUCING IOVERSOL MALLINCKRODT MEDICAL INC (US) 2000-08-02 EP claimed
EP-0886634-A1 PROCESS FOR PRODUCING IOVERSOL MALLINCKRODT MEDICAL, INC. (US) 1998-12-30 EP claimed
EP-0839056-A1 PROCESS FOR PRODUCING IOVERSOL MALLINCKRODT MEDICAL, INC. (US) 1998-05-06 EP claimed
WO-1997027172-A1 PROCESS FOR PRODUCING IOVERSOL MALLINCKRODT MEDICAL, INC. (US) 1997-07-31 WO claimed
WO-1996040286-A1 PROCESS FOR PRODUCING IOVERSOL MALLINCKRODT MEDICAL, INC. (US) 1996-12-19 WO claimed
CN-116421744-B Absorbable medical hydrogel and preparation method thereof 杭州融华再生医学科技有限公司 2024-02-09 CN disclosed
CN-116421744-A Absorbable medical hydrogel and preparation method thereof 杭州融华再生医学科技有限公司 2023-07-14 CN disclosed
US-6596904-B1 Process for producing ioversol MALLINC KRODT INC 2003-07-22 US disclosed
EP-0839056-B1 PROCESS FOR PRODUCING IOVERSOL MALLINCKRODT INC (US) 2003-05-07 EP disclosed
EP-0886634-B1 PROCESS FOR PRODUCING IOVERSOL MALLINCKRODT INC (US) 2002-04-24 EP disclosed
EP-0839056-A4 PROCESS FOR PRODUCING IOVERSOL MALLINCKRODT MEDICAL INC (US) 2000-09-13 EP disclosed
EP-0886634-A4 PROCESS FOR PRODUCING IOVERSOL MALLINCKRODT MEDICAL INC (US) 2000-08-02 EP disclosed
EP-0886634-A1 PROCESS FOR PRODUCING IOVERSOL MALLINCKRODT MEDICAL, INC. (US) 1998-12-30 EP disclosed
EP-0839056-A1 PROCESS FOR PRODUCING IOVERSOL MALLINCKRODT MEDICAL, INC. (US) 1998-05-06 EP disclosed
WO-1997027172-A1 PROCESS FOR PRODUCING IOVERSOL MALLINCKRODT MEDICAL, INC. (US) 1997-07-31 WO disclosed
US-5648536-A Process for producing ioversol LAFAYETTE PHARMACEUTICALS LLC 1997-07-15 US disclosed
WO-1996040286-A1 PROCESS FOR PRODUCING IOVERSOL MALLINCKRODT MEDICAL, INC. (US) 1996-12-19 WO disclosed