SCHEMBL502933

SCHEMBL502933

Brc1ccc(I)cn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15901316 0.82 METAP2 (0.38)
SCHEMBL20430469 0.72
SCHEMBL16841 0.71
SCHEMBL31243289 0.71
SCHEMBL4390590 0.71 CCR1 (0.46)
SCHEMBL198094 0.71
SCHEMBL18429796 0.70 APP (0.64)
SCHEMBL15907498 0.67 NPC1 (0.49)
SCHEMBL1151828 0.67
SCHEMBL19932456 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 737 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119264040-A Preparation method of 2,5 pyridine compound 苏州翔实医药发展有限公司 2025-01-07 CN claimed
CN-119264039-A Synthesis method of pyridine drug intermediate 苏州翔实医药发展有限公司 2025-01-07 CN claimed
CN-116284772-B Bipyridine triazole covalent organic polymer and preparation method and application thereof 四川大学 2024-02-27 CN claimed
CN-116284772-A Bipyridine triazole covalent organic polymer and preparation method and application thereof 四川大学 2023-06-23 CN claimed
CN-111499570-B Synthesis method of AV-45 intermediate 中国医学科学院放射医学研究所 2023-05-16 CN claimed
CN-111499570-A Synthetic method of AV-45 intermediate 中国医学科学院放射医学研究所 2020-08-07 CN claimed
CN-102432529-A Styryl pyridine disulfide dinitrogen derivative and preparation method thereof JIANGSU INST NUCLEAR MEDICINE 2012-05-02 CN claimed
EP-4107166-B1 HETEROARYL COMPOUNDS FOR TREATMENT OF COMPLEMENT FACTOR D MEDIATED DISORDERS ACHILLION PHARMACEUTICALS INC (US) 2026-05-27 EP disclosed
EP-4027995-B1 HPK1 ANTAGONISTS AND USES THEREOF NIMBUS SATURN INC (US) 2026-05-27 EP disclosed
EP-4741392-A1 1H-PYRAZOLO[4,3-C]PYRIDINE COMPOUND, AND COMPOSITION THEREOF AND USE THEREOF Shenzhen TargetRx Co., Ltd. (CN) 2026-05-13 EP disclosed
EP-3911640-B1 PCSK9 INHIBITORS FOR USE IN THERAPY, ESPECIALLY THE TREATMENT OF CARDIOVASCULAR DISEASE ASTRAZENECA AB (SE) 2026-05-13 EP disclosed
EP-4737448-A1 SARM1 ENZYME ACTIVITY INHIBITOR AND USE THEREOF Artivila (ShenZhen) Innovation Center, Ltd. (CN) 2026-05-06 EP disclosed
EP-4737455-A1 COMPOUND CONTAINING MULTI-FUSED RING STRUCTURE Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) 2026-05-06 EP disclosed
WO-1998028317-A2 SYNTHESIS OF NUCLEOSIDES AND POLYNUCLEOTIDES RIBOZYME PHARMACEUTICALS, INC. (US) 1998-07-02 WO disclosed
EP-0518636-A1 Liquid crystal compounds and compositions SANYO CHEMICAL INDUSTRIES LTD. (JP) 1992-12-16 EP disclosed
EP-0500210-A2 Liquid crystal compounds and compositions SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1992-08-26 EP disclosed
US-4973736-A Diethers of m- or p-hydroxyphenol BASF AKTIENGESELLSCHAFT (DE) 1990-11-27 US disclosed
EP-0083010-B1 DIETHERS OF M- OR P-HYDROXYPHENOLS AND PROCESS FOR PREPARING DIETHERS OR MONOETHERS OF M- OR P-HYDROXYPHENOLS BASF Aktiengesellschaft (DE) 1985-12-04 EP disclosed
EP-0083010-A1 Diethers of m- or p-hydroxyphenols and process for preparing diethers or monoethers of m- or p-hydroxyphenols BASF Aktiengesellschaft (DE) 1983-07-06 EP disclosed
US-4185152-A ANTIRADIATION AGENTS WARNER-LAMBERT COMPANY (US) 1980-01-22 US disclosed