Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | LHCGR | P22888 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5025541 | 0.87 | MTNR1A (0.45) | MTNR1AMTNR1BADORA2AALDH1A1RAB9A | |
| SCHEMBL5027966 | 0.82 | MTNR1A (0.43) | MTNR1AMTNR1BADORA2AALDH1A1RAB9A | |
| SCHEMBL5025527 | 0.78 | CNR1 (0.48) | MTNR1AMTNR1BADORA2AALDH1A1RAB9A | |
| SCHEMBL5023892 | 0.76 | MTNR1A (0.49) | MTNR1AMTNR1BALDH1A1RAB9AFAAH | |
| SCHEMBL5138185 | 0.73 | FAAH (0.41) | MTNR1AMTNR1BALDH1A1RAB9AFAAH | |
| SCHEMBL3797385 | 0.72 | MTNR1A (0.47) | MTNR1AMTNR1BADORA2AALDH1A1RAB9A | |
| SCHEMBL5025385 | 0.72 | FAAH (0.46) | MTNR1AMTNR1BALDH1A1RAB9AFAAH | |
| SCHEMBL5095607 | 0.72 | FAAH (0.46) | MTNR1AMTNR1BALDH1A1RAB9AFAAH | |
| SCHEMBL5138795 | 0.72 | FAAH (0.46) | MTNR1AMTNR1BALDH1A1RAB9AFAAH | |
| SCHEMBL3797272 | 0.71 | MTNR1A (0.46) | MTNR1AMTNR1BADORA2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362027-B1 | ACYLATED 6,7,8,9-TETRAHYDRO-5H-BENZOCYCLOHEPTENYL AMINES AND THEIR USE AS PHARMACEUTICAL | SANOFI AVENTIS DEUTSCHLAND (DE) | 2008-05-21 | — | — | EP | claimed |