Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | LHCGR | P22888 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5025541 | 0.81 | MTNR1A (0.45) | MTNR1AMTNR1BEPHX1ALDH1A1RAB9A | |
| SCHEMBL3795877 | 0.77 | MTNR1A (0.51) | MTNR1AMTNR1BALDH1A1HPGD | |
| SCHEMBL5025527 | 0.76 | CNR1 (0.48) | MTNR1AMTNR1BEPHX1ALDH1A1RAB9A | |
| SCHEMBL5029692 | 0.76 | MTNR1A (0.44) | MTNR1AMTNR1BEPHX1ALDH1A1RAB9A | |
| SCHEMBL5027966 | 0.75 | MTNR1A (0.43) | MTNR1AMTNR1BEPHX1ALDH1A1RAB9A | |
| SCHEMBL3801828 | 0.75 | MTNR1A (0.49) | MTNR1AMTNR1BALDH1A1RAB9ALMNA | |
| SCHEMBL5138185 | 0.75 | FAAH (0.41) | MTNR1AMTNR1BALDH1A1RAB9ALMNA | |
| SCHEMBL3797551 | 0.74 | ALDH1A1 (0.49) | MTNR1AMTNR1BALDH1A1HPGD | |
| SCHEMBL3797548 | 0.74 | ALDH1A1 (0.49) | MTNR1AMTNR1BALDH1A1HPGD | |
| SCHEMBL3388818 | 0.72 | MTNR1A (0.62) | MTNR1AMTNR1BRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362027-B1 | ACYLATED 6,7,8,9-TETRAHYDRO-5H-BENZOCYCLOHEPTENYL AMINES AND THEIR USE AS PHARMACEUTICAL | SANOFI AVENTIS DEUTSCHLAND (DE) | 2008-05-21 | — | — | EP | claimed |