Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16211974 | 0.76 | DNM1 (0.47) | DNM1ALDH1A1ALDH2CA12CA1 | |
| SCHEMBL2975409 | 0.72 | — | — | |
| SCHEMBL25140620 | 0.71 | — | — | |
| SCHEMBL520067 | 0.70 | CA12 (0.33) | DNM1ALDH1A1ALDH2CA12CA1 | |
| SCHEMBL865548 | 0.69 | MMP1 (0.36) | DNM1ALDH1A1ALDH2CA12CA1 | |
| SCHEMBL28581450 | 0.69 | DNM1 (0.63) | DNM1ALDH1A1ALDH2CA12CA1 | |
| SCHEMBL19144119 | 0.69 | DNM1 (0.41) | DNM1ALDH1A1ALDH2CA12CA1 | |
| SCHEMBL572057 | 0.69 | MEN1 (0.48) | DNM1ALDH1A1ALDH2CA12CA1 | |
| Hydrochloric Acid SCHEMBL1428262 | 0.67 | DNM1 (0.38) | DNM1ALDH1A1ALDH2CA12CA1 | |
| Bromide SCHEMBL31364322 | 0.67 | DNM1 (0.38) | DNM1ALDH1A1ALDH2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492462-A1 | AMINO PYRIMIDINE COMPOUND FOR INHIBITING PROTEIN TYROSINE KINASE ACTIVITY | Shenzhen Targetrx, Inc. (CN) | 2019-06-05 | — | — | EP | disclosed |
| EP-1999167-A2 | ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR | Novolen Technology Holdings, C.V. (NL) | 2008-12-10 | — | — | EP | disclosed |
| WO-2007106348-A2 | ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR | NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) | 2007-09-20 | — | — | WO | disclosed |