Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
| ▸ | EPHB3 | P54753 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17320982 | 0.81 | EPHB3 (0.56) | TGFBR1EPHB3ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL3612196 | 0.81 | CA12 (0.46) | EPHB3MAPTKDM4EALOX15TSHR | |
| SCHEMBL19786566 | 0.81 | EPHB3 (0.44) | EPHB3ALDH1A1SMN1; SMN2GAAMAPT | |
| SCHEMBL25336177 | 0.80 | EPHB3 (0.44) | EPHB3ALDH1A1GAAMAPTKDM4E | |
| SCHEMBL3612887 | 0.80 | EPHB3 (0.61) | EPHB3ALDH1A1MAPTKDM4EALOX15 | |
| SCHEMBL2176212 | 0.79 | NPC1 (0.49) | EPHB3ALDH1A1SMN1; SMN2GAAMAPT | |
| SCHEMBL12689690 | 0.79 | SMN1; SMN2 (0.47) | EPHB3ALDH1A1SMN1; SMN2GAAMAPT | |
| SCHEMBL25367703 | 0.79 | ALDH1A1 (0.45) | EPHB3ALDH1A1SMN1; SMN2GAAMAPT | |
| SCHEMBL2174798 | 0.78 | IRAK4 (0.44) | EPHB3ALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL23873083 | 0.78 | EPHB3 (0.42) | EPHB3ALDH1A1MAPTKDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080262027-A1 | Novel Chemical Compounds | DUFFY KEVIN J | 2008-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080262027-A1 | Novel Chemical Compounds | HIPK3, DAPK3, YARS1 | TGFBR1 4796/4885EPHB3 3374/4885ALDH1A1 4196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.