Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 3/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL27622315 | 0.94 | LMNA (0.53) | LMNAALDH1A1SLC22A16THRBOR51E2 | |
| Glycerin SCHEMBL6009743 | 0.93 | LMNA (0.60) | LMNAALDH1A1SLC22A16THRBOR51E2 | |
| Glycerin SCHEMBL27520568 | 0.93 | LMNA (0.60) | LMNAALDH1A1SLC22A16THRBOR51E2 | |
| Glycerin SCHEMBL4630792 | 0.93 | LMNA (0.60) | LMNAALDH1A1SLC22A16THRBOR51E2 | |
| Glycerin SCHEMBL9509912 | 0.93 | LMNA (0.60) | LMNAALDH1A1SLC22A16THRBOR51E2 | |
| Glycerin SCHEMBL27990518 | 0.90 | LMNA (0.56) | LMNAALDH1A1SLC22A16THRBOR51E2 | |
| Glycerin SCHEMBL10693196 | 0.88 | LMNA (0.53) | LMNAALDH1A1SLC22A16THRBOR51E2 | |
| Glycerin SCHEMBL10693194 | 0.88 | LMNA (0.53) | LMNAALDH1A1SLC22A16THRBOR51E2 | |
| Glycerin SCHEMBL17763427 | 0.85 | LMNA (0.50) | LMNAALDH1A1SLC22A16THRBOR51E2 | |
| Glycerin SCHEMBL2938480 | 0.84 | LMNA (0.56) | LMNAALDH1A1SLC22A16THRBOR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0062298-A2 | Heat hardening sealant for flexible couplings | FIBERGLAS CANADA Inc. (CA) | 1982-10-13 | — | — | EP | claimed |
| WO-2023119134-A1 | SUBSTRATE MATERIAL COMPRISING BEADS FOR AEROSOL DELIVERY DEVICES | Nicoventures Trading Limited (GB) | 2023-06-29 | — | — | WO | disclosed |
| US-20230189877-A1 | SUBSTRATE MATERIAL COMPRISING BEADS FOR AEROSOL DELIVERY DEVICES | NICOVENTURES TRADING LTD (GB) | 2023-06-22 | — | — | US | disclosed |
| US-10395633-B2 | Sound insulating sheet material with a cellular structure including gelatine and/or a process for producing the same | ACOUSTIC SPACE PTY LTD (AU) | 2019-08-27 | — | — | US | disclosed |
| EP-2994581-B1 | A SOUND INSULATING SHEET MATERIAL WITH A CELLULAR STRUCTURE INCLUDING GELATINE AND/OR A PROCESS FOR PRODUCING THE SAME | ACOUSTIC SPACE PTY LTD (AU) | 2019-03-13 | — | — | EP | disclosed |
| US-20170263234-A1 | SOUND INSULATING SHEET MATERIAL WITH A CELLULAR STRUCTURE INCLUDING GELATINE AND/OR A PROCESS FOR PRODUCING THE SAME | ACOUSTIC SPACE PTY LTD (AU) | 2017-09-14 | — | — | US | disclosed |
| EP-3086751-A1 | STABILIZED STANNOUS COMPOSITIONS | The University Of Melbourne (AU) | 2016-11-02 | — | — | EP | disclosed |
| EP-2994581-A1 | A SOUND INSULATING SHEET MATERIAL WITH A CELLULAR STRUCTURE INCLUDING GELATINE AND/OR A PROCESS FOR PRODUCING THE SAME | Acoustic Space Pty Ltd (AU) | 2016-03-16 | — | — | EP | disclosed |
| WO-2015095932-A1 | STABILIZED STANNOUS COMPOSITIONS | THE UNIVERSITY OF MELBOURNE (AU) | 2015-07-02 | — | — | WO | disclosed |
| WO-2014179844-A1 | A SOUND INSULATING SHEET MATERIAL WITH A CELLULAR STRUCTURE INCLUDING GELATINE AND/OR A PROCESS FOR PRODUCING THE SAME | ACOUSTIC SPACE PTY LTD (AU) | 2014-11-13 | — | — | WO | disclosed |
| EP-1986587-A1 | FLUORIDE COMPOSITION AND METHODS FOR DENTAL MINERALIZATION | THE UNIVERSITY OF MELBOURNE (AU) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007090242-A1 | FLUORIDE COMPOSITION AND METHODS FOR DENTAL MINERALIZATION | THE UNIVERSITY OF MELBOURNE (AU) | 2007-08-16 | — | — | WO | disclosed |
| CN-1230153-C | Film Coated tablet compositions having enhanced disintegration characteristics | MCNEIL PPC INC (US) | 2005-12-07 | — | — | CN | disclosed |