Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.43 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 3/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL28637598 | 0.94 | LMNA (0.56) | LMNAALDH1A1OR51E2SLC22A16SLC22A6 | |
| Glycerin SCHEMBL27520568 | 0.90 | LMNA (0.60) | LMNAALDH1A1OR51E2SLC22A16SLC22A6 | |
| Glycerin SCHEMBL9509912 | 0.90 | LMNA (0.60) | LMNAALDH1A1OR51E2SLC22A16SLC22A6 | |
| Glycerin SCHEMBL27571427 | 0.89 | LMNA (0.45) | LMNAALDH1A1OR51E2SLC22A16CA2 | |
| Glycerin SCHEMBL27569897 | 0.87 | TDP1 (0.48) | LMNAALDH1A1OR51E2SLC22A16CA4 | |
| Glycerin SCHEMBL15453340 | 0.85 | LMNA (0.53) | LMNAALDH1A1OR51E2SLC22A16THRB | |
| Glycerin SCHEMBL27622315 | 0.85 | LMNA (0.53) | LMNAALDH1A1OR51E2SLC22A16THRB | |
| Glycerin SCHEMBL6009743 | 0.84 | LMNA (0.60) | LMNAALDH1A1OR51E2SLC22A16SLC22A6 | |
| Glycerin SCHEMBL5030995 | 0.84 | LMNA (0.60) | LMNAALDH1A1OR51E2SLC22A16SLC22A6 | |
| Glycerin SCHEMBL4630792 | 0.84 | LMNA (0.60) | LMNAALDH1A1OR51E2SLC22A16SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115926014-A | Extraction method of fritillaria polysaccharide | 西藏天虹科技股份有限责任公司 | 2023-04-07 | — | — | CN | claimed |
| CN-114807113-B | Preparation method of embedded biological enzyme preparation | 南京永正生物科技有限公司 | 2022-10-14 | — | — | CN | claimed |
| CN-112807324-A | Cactus polysaccharide composition, blood pressure lowering medicine and health food | 郑仙兰 | 2021-05-18 | — | — | CN | claimed |
| CN-102119917-A | Preparation method of recombinant human endostatin temperature sensitive gel | JIANGSU SIMCERE PHARM RES CO | 2011-07-13 | — | — | CN | claimed |
| CN-115926014-A | Extraction method of fritillaria polysaccharide | 西藏天虹科技股份有限责任公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-114807113-B | Preparation method of embedded biological enzyme preparation | 南京永正生物科技有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-111012741-B | Fluconazole ear drops and preparation method thereof | 广州博济医药生物技术股份有限公司 | 2021-06-08 | — | — | CN | disclosed |
| CN-112806502-A | Plant health-care beverage | 郑仙兰 | 2021-05-18 | — | — | CN | disclosed |
| CN-112807324-A | Cactus polysaccharide composition, blood pressure lowering medicine and health food | 郑仙兰 | 2021-05-18 | — | — | CN | disclosed |
| CN-212722260-U | Sample extraction device for detecting atmospheric pollutant fluoride | 泰安三英环境安全检测有限公司 | 2021-03-16 | — | — | CN | disclosed |
| CN-111012741-A | Fluconazole ear drops and preparation method thereof | 广州博济医药生物技术股份有限公司 | 2020-04-17 | — | — | CN | disclosed |
| CN-108249812-A | A kind of slow-release solid water-reducing agent based on haydite and preparation method thereof | 洛阳理工学院 | 2018-07-06 | — | — | CN | disclosed |
| EP-2606819-B1 | Measurement of chemical equilibrium ratio using a magnetic resonance spectroscopy system | GEN ELECTRIC (US) | 2017-06-28 | — | — | EP | disclosed |
| US-8933697-B2 | Measurement of chemical equilibrium ratio using a magnetic resonance spectroscopy system | GENERAL ELECTRIC COMPANY (US) | 2015-01-13 | — | — | US | disclosed |
| EP-2606819-A1 | Measurement of chemical equilibrium ratio using a magnetic resonance spectroscopy system | General Electric Company (US) | 2013-06-26 | — | — | EP | disclosed |
| US-20130154637-A1 | MEASUREMENT OF CHEMICAL EQUILIBRIUM RATIO USING A MAGNETIC RESONANCE SPECTROSCOPY SYSTEM | GENERAL ELECTRIC COMPANY (US) | 2013-06-20 | — | — | US | disclosed |
| CN-102119917-A | Preparation method of recombinant human endostatin temperature sensitive gel | JIANGSU SIMCERE PHARM RES CO | 2011-07-13 | — | — | CN | disclosed |
| CN-101730524-A | A foam material for medical use and method for producing same | SMITH & NEPHEW | 2010-06-09 | — | — | CN | disclosed |
| EP-2148654-A2 | A FOAM MATERIAL FOR MEDICAL USE AND METHOD FOR PRODUCING SAME | Smith & Nephew PLC (GB) | 2010-02-03 | — | — | EP | disclosed |
| WO-2008129318-A2 | A FOAM MATERIAL FOR MEDICAL USE AND METHOD FOR PRODUCING SAME | SMITH & NEPHEW PLC (GB) | 2008-10-30 | — | — | WO | disclosed |