Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 4/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.38 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL27520568 | 1.00 | LMNA (0.60) | LMNAALDH1A1SLC22A16THRBCA4 | |
| Glycerin SCHEMBL27622315 | 0.94 | LMNA (0.53) | LMNAALDH1A1SLC22A16THRBCA4 | |
| Glycerin SCHEMBL5030995 | 0.93 | LMNA (0.60) | LMNAALDH1A1SLC22A16THRBCA4 | |
| Glycerin SCHEMBL6009743 | 0.93 | LMNA (0.60) | LMNAALDH1A1SLC22A16THRBCA4 | |
| Glycerin SCHEMBL4630792 | 0.93 | LMNA (0.60) | LMNAALDH1A1SLC22A16THRBCA4 | |
| Glycerin SCHEMBL27990518 | 0.90 | LMNA (0.56) | LMNAALDH1A1SLC22A16THRBCA4 | |
| Glycerin SCHEMBL2938480 | 0.90 | LMNA (0.56) | LMNAALDH1A1SLC22A16THRBCA4 | |
| Glycerin SCHEMBL15453340 | 0.88 | LMNA (0.53) | LMNAALDH1A1SLC22A16THRBCA4 | |
| SCHEMBL7465722 | 0.85 | — | — | |
| Glycerin SCHEMBL17763427 | 0.85 | LMNA (0.50) | LMNAALDH1A1SLC22A16THRBCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0291870-B1 | PROCESS FOR THE PRODUCTION OF TRIGLYCERIDES | Henkel Kommanditgesellschaft auf Aktien (DE) | 1993-09-22 | — | — | EP | claimed |
| US-5254722-A | Process for the production of triglycerides | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1993-10-19 | — | — | US | disclosed |