Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.43 |
| ▸ | RARA | P10276 | 2/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6402665 | 0.84 | RARB (0.41) | RARBRARARARGMCL1KIF11 | |
| SCHEMBL502692 | 0.82 | RARB (0.45) | RARBRARARARGMCL1KIF11 | |
| SCHEMBL9399833 | 0.81 | RARB (0.48) | RARBRARARARGMCL1KIF11 | |
| SCHEMBL16377225 | 0.81 | RARB (0.48) | RARBRARARARGMCL1KIF11 | |
| SCHEMBL9625064 | 0.81 | MCL1 (0.41) | RARBRARAMCL1ALOX5NPC1 | |
| SCHEMBL502961 | 0.81 | RARB (0.40) | RARBRARARARGMCL1KIF11 | |
| SCHEMBL9664954 | 0.80 | RARB (0.47) | RARBRARARARGMCL1KIF11 | |
| SCHEMBL16377206 | 0.80 | RARB (0.50) | RARBRARARARGMCL1KIF11 | |
| SCHEMBL17487380 | 0.79 | CHKA (0.36) | RARBMCL1ALOX5LPLLIPG | |
| SCHEMBL15868561 | 0.78 | RARB (0.44) | RARBRARARARGMCL1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8372975-B2 | Liquid crystal compound having difluoropropenyleneoxy bonding group | JNC CORPORATION (JP) | 2013-02-12 | — | — | US | disclosed |
| US-8372975-B2 | Liquid crystal compound having difluoropropenyleneoxy bonding group | JNC CORPORATION (JP) | 2013-02-12 | — | — | US | disclosed |
| US-8372975-B2 | Liquid crystal compound having difluoropropenyleneoxy bonding group | JNC CORPORATION (JP) | 2013-02-12 | — | — | US | disclosed |
| US-20120029194-A1 | LIQUID CRYSTAL COMPOUND HAVING DIFLUOROPROPENYLENEOXY BONDING GROUP | CHISSO PETROCHEMICAL CORPORATION (JP) | 2012-02-02 | — | — | US | disclosed |
| US-20120029194-A1 | LIQUID CRYSTAL COMPOUND HAVING DIFLUOROPROPENYLENEOXY BONDING GROUP | CHISSO PETROCHEMICAL CORPORATION (JP) | 2012-02-02 | — | — | US | disclosed |
| US-20120029194-A1 | LIQUID CRYSTAL COMPOUND HAVING DIFLUOROPROPENYLENEOXY BONDING GROUP | CHISSO PETROCHEMICAL CORPORATION (JP) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029194-A1 | LIQUID CRYSTAL COMPOUND HAVING DIFLUOROPROPENYLENEOXY BONDING GROUP | LEF1, EIF4A3, TCF4 | RARB 3142/4885RARA 2088/4885RARG 3356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.