Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LPL | P06858 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | CHKA | P35790 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL502961 | 0.91 | RARB (0.40) | RARBRARARARGMCL1KIF11 | |
| SCHEMBL503184 | 0.84 | RARB (0.43) | RARBRARARARGMCL1KIF11 | |
| SCHEMBL16039309 | 0.83 | RARB (0.46) | RARBRARARARGMCL1KIF11 | |
| SCHEMBL9625064 | 0.82 | MCL1 (0.41) | RARBRARAMCL1NPC1RAB9A | |
| SCHEMBL6409307 | 0.82 | RARB (0.43) | RARBRARARARGMCL1KIF11 | |
| SCHEMBL10030218 | 0.81 | RARB (0.50) | RARBRARARARGTP53HSD17B10 | |
| SCHEMBL12656525 | 0.78 | RARB (0.43) | RARBRARARARGMCL1NPC1 | |
| SCHEMBL15868561 | 0.76 | RARB (0.44) | RARBRARARARGMCL1KIF11 | |
| SCHEMBL16038459 | 0.76 | MCL1 (0.49) | RARBRARARARGMCL1NPC1 | |
| SCHEMBL9624346 | 0.76 | MCL1 (0.41) | RARBRARAMCL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6864397-B2 | Difluoromethyl ether derivative and process for producing the same | CHISSO CORPORATION (JP) | 2005-03-08 | — | — | US | disclosed |
| US-6827876-B2 | Using alpha, alpha -difluorocyclohexylidene derivative as starting material to obtain difluoromethyl ether derivative | CHISSO CORPORATION (JP) | 2004-12-07 | — | — | US | disclosed |
| US-20040016906-A1 | Difluoromethyl ether derivative and process for producing the same | JNC CORPORATION (JP) | 2004-01-29 | — | — | US | disclosed |
| US-20040004207-A1 | Difluoromethyl ether derivative and process for producing the same | JNC CORPORATION (JP) | 2004-01-08 | — | — | US | disclosed |
| US-6605747-B2 | Reacting the starting material, an alpha , alpha -difluorocyclohexylidene derivative with a halogen to produce an intermediate, reacting the intermediate with a phenol compound in presence of a base | CHISSO CORPORATION (JP) | 2003-08-12 | — | — | US | disclosed |
| US-20020120168-A1 | Difluoromethyl ether derivative and process for producing the same | JNC PETROCHEMICAL CORPORATION (JP) | 2002-08-29 | — | — | US | disclosed |
| EP-1182186-A2 | Difluoromethyl ether derivative and process for producing the same | CHISSO CORPORATION (JP) | 2002-02-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040004207-A1 | Difluoromethyl ether derivative and process for producing the same | RCC1, PYM1, SCFD1 | RARB 3277/4885RARA 2698/4885RARG 3554/4885 |
| US-20040016906-A1 | Difluoromethyl ether derivative and process for producing the same | RCC1, SCFD1, AFF1 | RARB 3298/4885RARA 2721/4885RARG 3614/4885 |
| US-20020120168-A1 | Difluoromethyl ether derivative and process for producing the same | LEF1, AFF1, RCC1 | RARB 2584/4885RARA 2060/4885RARG 2720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.