Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 11/20 | 0.64 |
| ▸ | PGK1 | P00558 | 3/20 | 0.58 |
| ▸ | PGK2 | P07205 | 3/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582374 | 0.92 | ADORA3 (0.63) | ADORA3PGK1PGK2ADORA1ADORA2A | |
| SCHEMBL6270221 | 0.86 | ADORA3 (0.57) | ADORA3PGK1PGK2ADORA1ADORA2A | |
| SCHEMBL5380408 | 0.82 | ADORA3 (0.65) | ADORA3PGK1PGK2ADORA1ADORA2A | |
| SCHEMBL5385714 | 0.82 | ADORA3 (0.54) | ADORA3PGK1PGK2ADORA1ADORA2A | |
| SCHEMBL5032145 | 0.81 | ADORA3 (0.58) | ADORA3PGK1PGK2ADORA1ADORA2A | |
| SCHEMBL5038188 | 0.80 | ADORA3 (0.59) | ADORA3PGK1PGK2ADORA1ADORA2A | |
| SCHEMBL5034054 | 0.80 | ADORA3 (0.59) | ADORA3PGK1PGK2ADORA1ADORA2A | |
| SCHEMBL5035415 | 0.80 | ADORA3 (0.59) | ADORA3PGK1PGK2ADORA1ADORA2A | |
| SCHEMBL5397146 | 0.79 | ADORA3 (0.58) | ADORA3PGK1PGK2ADORA1ADORA2A | |
| SCHEMBL5040344 | 0.79 | ADORA3 (0.59) | ADORA3PGK1PGK2ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414837-A1 | ADENOSINE A3 RECEPTOR AGONISTS | CV THERAPEUTICS, INC. (US) | 2004-05-06 | — | — | EP | claimed |
| WO-2003014137-A1 | ADENOSINE A3 RECEPTOR AGONISTS | CV THERAPEUTICS, INC. (US) | 2003-02-20 | — | — | WO | claimed |