SCHEMBL5032529

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5041346	0.93	CYP3A4 (0.39)	CYP3A4TSHRGAANPSR1HPGD
	SCHEMBL5032514	0.93	CYP3A4 (0.43)	CYP3A4TSHRGAANPSR1HPGD
	SCHEMBL5032512	0.89	CYP3A4 (0.40)	CYP3A4TSHRGAANPSR1HPGD
	SCHEMBL5035234	0.89	ALDH1A1 (0.41)	CYP3A4TSHRHPGDRAB9AALDH1A1
	SCHEMBL5034781	0.88	CYP3A4 (0.42)	CYP3A4TSHRGAANPSR1HPGD
	SCHEMBL5035170	0.85	CYP3A4 (0.36)	CYP3A4TSHRGAANPSR1HPGD
	SCHEMBL14190190	0.85	FLT1 (0.41)	CYP3A4TSHRRAB9AMAPTFLT1
	SCHEMBL5035233	0.83	CYP3A4 (0.38)	CYP3A4TSHRGAANPSR1HPGD
	SCHEMBL5035256	0.83	KMT2A (0.41)	TSHRGAAHPGDNPC1RAB9A
	SCHEMBL5032526	0.83	CYP3A4 (0.49)	CYP3A4GAANPSR1HPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.