SCHEMBL5035234

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5032529	0.89	CYP3A4 (0.43)	ALDH1A1HPGDFLT1FLT4KDR
	SCHEMBL5032514	0.89	CYP3A4 (0.43)	ALDH1A1HPGDFLT1FLT4KDR
	SCHEMBL14190190	0.88	FLT1 (0.41)	FLT1FLT4KDRTTRMRGPRX4
	SCHEMBL5032512	0.87	CYP3A4 (0.40)	ALDH1A1HPGDFLT1FLT4KDR
	SCHEMBL5035193	0.86	HPGD (0.47)	ALDH1A1HPGDMRGPRX4TSHRCYP1A2
	SCHEMBL5035256	0.86	KMT2A (0.41)	ALDH1A1HPGDTSHRCYP1A2CYP2C9
	SCHEMBL5035170	0.85	CYP3A4 (0.36)	ALDH1A1HPGDFLT1FLT4KDR
	SCHEMBL5041346	0.84	CYP3A4 (0.39)	ALDH1A1HPGDFLT1FLT4KDR
	SCHEMBL5036600	0.84	HPGD (0.43)	HPGDKDM4EL3MBTL1MAPTRAB9A
	SCHEMBL5034848	0.83	HSD11B1 (0.41)	ALDH1A1HPGDFLT1FLT4KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.