SCHEMBL5032653

SCHEMBL5032653

Cc1ccc(C(=O)N(C(N)=O)c2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.48
CES1 P23141 2/20 0.48
MEN1 O00255 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
KMT2A Q03164 1/20 0.44
ALDH1A1 P00352 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
PKM P14618 1/20 0.44
HSD17B1 P14061 1/20 0.42
HSD17B2 P37059 1/20 0.42
CYP2D6 P10635 1/20 0.42
HIF1A Q16665 1/20 0.42
AKR1C3 P42330 1/20 0.42
KDM4E B2RXH2 1/20 0.41
HPGD P15428 1/20 0.41
LMNA P02545 2/20 0.41
POLB P06746 1/20 0.41
USP2 O75604 1/20 0.41
TRPM8 Q7Z2W7 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4837185 1.00 CES2 (0.48) CES2CES1MEN1NPC1RAB9A
SCHEMBL6037561 0.93 CES2 (0.48) CES2CES1MEN1NPC1RAB9A
SCHEMBL2995400 0.89 CES2 (0.55) CES2CES1MEN1NPC1RAB9A
Benzoylphenylurea SCHEMBL83109 0.87 L3MBTL1 (0.48) CES2CES1RAB9AKMT2AALDH1A1
Benzoylphenylurea SCHEMBL31707309 0.85 TDP1 (0.46) CES2CES1NPC1RAB9AKMT2A
SCHEMBL11254594 0.79 CES2 (0.52) CES2CES1MEN1NPC1RAB9A
SCHEMBL6311793 0.78 CES2 (0.55) CES2CES1MEN1NPC1RAB9A
SCHEMBL6830626 0.77 ALDH1A1 (0.42) CES2CES1MEN1NPC1RAB9A
SCHEMBL28406694 0.77 CES2 (0.50) CES2CES1MEN1NPC1RAB9A
Hydrochloric Acid SCHEMBL11834225 0.77 CES2 (0.50) CES2CES1MEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7449287-B1 Pearlescent textured imaging supports EASTMAN KODAK COMPANY (US) 2008-11-11 US disclosed