Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.49 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5031908 | 0.86 | PPARA (0.41) | HPGDLMNAADRB2TP53MEN1 | |
| SCHEMBL5032777 | 0.82 | ANO1 (0.49) | ANO1ANO2HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL5034466 | 0.79 | HTT (0.43) | HPGDLMNAALDH1A1KMT2A | |
| SCHEMBL5037057 | 0.78 | PPARA (0.39) | HPGDLMNAALDH1A1KDM4ETP53 | |
| SCHEMBL5032820 | 0.78 | PPARA (0.40) | HPGDALDH1A1 | |
| SCHEMBL5029970 | 0.77 | PPARA (0.44) | HPGDSMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL5034465 | 0.77 | PPARA (0.48) | RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5031737 | 0.77 | PPARA (0.41) | — | |
| SCHEMBL5032738 | 0.76 | PPARA (0.40) | HPGDLMNAALDH1A1 | |
| SCHEMBL5034526 | 0.76 | PPARA (0.47) | RAB9ASMN1; SMN2LMNAKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |