Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 18/20 | 0.48 |
| ▸ | PPARD | Q03181 | 17/20 | 0.48 |
| ▸ | PPARG | P37231 | 15/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5032977 | 0.85 | PPARA (0.61) | PPARAPPARDPPARG | |
| SCHEMBL5032738 | 0.82 | PPARA (0.40) | PPARAPPARDPPARGALDH1A1 | |
| SCHEMBL5031908 | 0.82 | PPARA (0.41) | PPARAPPARDPPARG | |
| SCHEMBL5034466 | 0.81 | HTT (0.43) | PPARAPPARDPPARGALDH1A1 | |
| SCHEMBL5029970 | 0.81 | PPARA (0.44) | PPARAPPARDPPARGALDH1A1SMN1; SMN2 | |
| SCHEMBL6427520 | 0.81 | PPARA (0.48) | PPARAPPARDPPARGNPC1ALDH1A1 | |
| SCHEMBL5032817 | 0.79 | PPARD (0.47) | PPARAPPARDPPARGALDH1A1 | |
| SCHEMBL5034503 | 0.79 | PPARA (0.61) | PPARAPPARDPPARG | |
| SCHEMBL5032820 | 0.78 | PPARA (0.40) | PPARAPPARDPPARGNPC1ALDH1A1 | |
| SCHEMBL5031737 | 0.77 | PPARA (0.41) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |