Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5030063 | 0.90 | CHRM3 (0.42) | HPGDALDH1A1NPC1RAB9APOLB | |
| SCHEMBL5029832 | 0.86 | ALDH1A1 (0.39) | HPGDGAAALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL5032948 | 0.86 | ALDH1A1 (0.43) | LMNAHPGDALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL5034494 | 0.85 | ALDH1A1 (0.42) | LMNAHPGDGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL5032956 | 0.85 | HRH3 (0.38) | ALDH1A1SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL5031908 | 0.83 | PPARA (0.41) | LMNAHPGDRECQLMEN1KMT2A | |
| SCHEMBL5034484 | 0.78 | LMNA (0.43) | LMNAHTTHPGDTMEM97SIGMAR1 | |
| SCHEMBL5032938 | 0.77 | PPARA (0.49) | LMNAHPGDGAASMN1; SMN2NPC1 | |
| SCHEMBL5034466 | 0.75 | HTT (0.43) | LMNAHTTHPGDGAAALDH1A1 | |
| SCHEMBL5029970 | 0.75 | PPARA (0.44) | LMNAHTTHPGDGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |