Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.88 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.88 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.88 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.88 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.88 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.88 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.88 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.88 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.88 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.88 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.88 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.75 |
| ▸ | LMNA | P02545 | 2/20 | 0.75 |
| ▸ | MAPT | P10636 | 2/20 | 0.75 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.75 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6608564 | 0.98 | HDAC1 (0.84) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL517169 | 0.95 | HDAC1 (0.96) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL9356269 | 0.93 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL3378075 | 0.93 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL3383102 | 0.93 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL6604478 | 0.93 | HDAC1 (0.92) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL7824358 | 0.93 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL9352420 | 0.93 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL9663087 | 0.93 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL3381106 | 0.93 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 471 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151884-A1 | USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE | PARSONS C LOWELL (US) | 2025-07-17 | — | — | WO | claimed |
| US-11884628-B2 | Method for synthesizing lactam derivatives without use of catalyst | GUIZHOU UNIVERSITY (CN) | 2024-01-30 | — | — | US | claimed |
| US-20220177429-A1 | METHOD FOR SYNTHESIZING LACTAM DERIVATIVES WITHOUT USE OF CATALYST | GUIZHOU UNIVERSITY (CN) | 2022-06-09 | — | — | US | claimed |
| CN-112824392-A | Quinoline derivative and preparation method and application thereof | 中国农业大学 | 2021-05-21 | — | — | CN | claimed |
| WO-2020228170-A1 | CATALYST-FREE SYNTHESIS METHOD FOR LACTAM DERIVATIVE | 贵州大学 | 2020-11-19 | — | — | WO | claimed |
| CN-109942473-B | Method for synthesizing lactam derivative without catalyst | 贵州大学 | 2020-09-15 | — | — | CN | claimed |
| CN-107298640-B | Preparation method and application of methylene ketone compound | 曲阜师范大学 | 2020-08-04 | — | — | CN | claimed |
| CN-111004291-A | Etimicin derivative and synthetic method thereof | 卓和药业集团有限公司 | 2020-04-14 | — | — | CN | claimed |
| CN-111004292-A | Gentamicin derivative and preparation method thereof | 卓和药业集团有限公司 | 2020-04-14 | — | — | CN | claimed |
| CN-110845554-A | Synthesis method of etimicin sulfate | 卓和药业集团有限公司 | 2020-02-28 | — | — | CN | claimed |
| WO-2005113495-A1 | METHOD FOR PRODUCING DIPHENYL AZETIDINONE DERIVATIVES | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2005-12-01 | — | — | WO | claimed |
| WO-2005110970-A1 | OXO-SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | Grünenthal GmbH (DE) | 2005-11-24 | — | — | WO | claimed |
| US-6946025-B2 | Process for preparing tetra-amide compounds | XEROX CORPORATION (US) | 2005-09-20 | — | — | US | claimed |
| US-20050090690-A1 | Process for preparing tetra-amide compounds | XEROX CORPORATION | 2005-04-28 | — | — | US | claimed |
| US-6861550-B2 | Polyhydroxyalkanoate containing 3-hydroxybenzoylalkanoic acid as monomer unit, and method for producing the same | CANON KABUSHIKI KAISHA (JP) | 2005-03-01 | — | — | US | claimed |
| US-20030100084-A1 | Polyhydroxyalkanoate containing 3-hydroxybenzoylalkanoic acid as monomer unit, and method for producing the same | CANON KABUSHIKI KAISHA (JP) | 2003-05-29 | — | — | US | claimed |
| US-6398857-B1 | ACCUSTIC PIEZOELECTRIC; HOT MELT INK JET PRINTING; BENZOIC ACID VEHICLE; ALKYL OR PHENYL CARBOXYLIC ACID VISCOSITY MODIFIER; RETAINS DESIRED HARDNESS | XEROX CORPORATION | 2002-06-04 | — | — | US | claimed |
| EP-1130042-A2 | Polyhydroxyalkanoate containing 3-hydroxybenzoylalkanoic acid as monomer unit, and method for producing the same | CANON KABUSHIKI KAISHA (JP) | 2001-09-05 | — | — | EP | claimed |
| EP-0619290-B1 | Salts of alkaline earth metals and transition metals as well as complexes of transition metals of ketocarboxylic acids and their use as corrosion inhibitors | CIBA GEIGY AG (CH) | 1996-10-09 | — | — | EP | claimed |
| EP-0164101-B1 | BENZOYLPROPIONIC ACID DERIVATIVES, THEIR USE AND PHARMACEUTICAL COMPOSITIONS | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1988-09-07 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11884628-B2 | Method for synthesizing lactam derivatives without use of catalyst | COASY, SI, NAAA | HDAC1 1075/4885HDAC8 665/4885HDAC3 2248/4885 |
| US-20050090690-A1 | Process for preparing tetra-amide compounds | TAF9, TAF5, TAF1 | HDAC1 553/4885HDAC8 623/4885HDAC3 849/4885 |
| US-20220177429-A1 | METHOD FOR SYNTHESIZING LACTAM DERIVATIVES WITHOUT USE OF CATALYST | COASY, SI, NAAA | HDAC1 1075/4885HDAC8 665/4885HDAC3 2248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.