SCHEMBL517169

SCHEMBL517169

O=C(O)CCCCC(=O)c1ccccc1

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 6/20 0.96
HDAC8 Q9BY41 6/20 0.96
HDAC3 O15379 2/20 0.96
HDAC4 P56524 2/20 0.96
HDAC7 Q8WUI4 2/20 0.96
HDAC2 Q92769 2/20 0.96
HDAC10 Q969S8 2/20 0.96
HDAC11 Q96DB2 2/20 0.96
HDAC6 Q9UBN7 2/20 0.96
HDAC9 Q9UKV0 2/20 0.96
HDAC5 Q9UQL6 2/20 0.96
TDP1 Q9NUW8 3/20 0.83
MAPT P10636 3/20 0.83
L3MBTL1 Q9Y468 2/20 0.83
LMNA P02545 2/20 0.83
NR4A2 P43354 1/20 0.75
CYP2C19 P33261 2/20 0.67
ALDH1A1 P00352 1/20 0.67
GAA P10253 1/20 0.67
RAB9A P51151 2/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9352420 0.98 HDAC1 (1.00) HDAC1HDAC8HDAC3HDAC4HDAC7
SCHEMBL6604478 0.98 HDAC1 (0.92) HDAC1HDAC8HDAC3HDAC4HDAC7
SCHEMBL3381106 0.98 HDAC1 (1.00) HDAC1HDAC8HDAC3HDAC4HDAC7
SCHEMBL3383102 0.98 HDAC1 (1.00) HDAC1HDAC8HDAC3HDAC4HDAC7
SCHEMBL3378075 0.98 HDAC1 (1.00) HDAC1HDAC8HDAC3HDAC4HDAC7
SCHEMBL9356269 0.98 HDAC1 (1.00) HDAC1HDAC8HDAC3HDAC4HDAC7
SCHEMBL7824358 0.98 HDAC1 (1.00) HDAC1HDAC8HDAC3HDAC4HDAC7
SCHEMBL9663087 0.98 HDAC1 (1.00) HDAC1HDAC8HDAC3HDAC4HDAC7
SCHEMBL503304 0.95 HDAC1 (0.88) HDAC1HDAC8HDAC3HDAC4HDAC7
SCHEMBL6608564 0.93 HDAC1 (0.84) HDAC1HDAC8HDAC3HDAC4HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1933 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3624854-B1 PROTEIN-DRUG CONJUGATES AND THEIR USE IN THE TREATMENT OF CANCERS UNIV STRASBOURG (FR) 2026-04-15 EP claimed
US-20260083866-A1 COMPOSITIONS TARGETING ENDOTHELIAL CELLS AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2026-03-26 US claimed
US-20260069697-A1 METHOD OF TREATING CANCER INTENSITY THERAPEUTICS INC (US) 2026-03-12 US claimed
EP-4658676-A2 ANTI-CDH17 ANTIBODIES AND USE OF THE SAME Bighat Biosciences, Inc. (US) 2025-12-10 EP claimed
EP-4642492-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE FUNCTIONAL SMALL MOLECULE COMPOUNDS FOR ENHANCED TREATMENT OF REFRACTORY DISEASES Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 EP claimed
EP-4642484-A1 TARGETED TREATMENT OF PROSTATE CANCERS AND OTHER TUMORS BY AN ANTIBODY-DRUG CONJUGATE Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 EP claimed
EP-4635516-A2 ANTI-EDB ANTIBODIES AND ANTIBODY-DRUG CONJUGATES Pfizer Inc. (US) 2025-10-22 EP claimed
EP-4633681-A1 AURISTATIN LINKER-PAYLOADS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF Merck Sharp & Dohme LLC (US) 2025-10-22 EP claimed
WO-2025151884-A1 USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE PARSONS C LOWELL (US) 2025-07-17 WO claimed
CN-120078904-A Conjugates of cytotoxic drugs and prodrug forms of the conjugates 辛迪维亚公司 2025-06-03 CN claimed
US-6861550-B2 Polyhydroxyalkanoate containing 3-hydroxybenzoylalkanoic acid as monomer unit, and method for producing the same CANON KABUSHIKI KAISHA (JP) 2005-03-01 US claimed
WO-2004089416-A2 COMBINATION OF AN 11BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITOR AND AN ANTIHYPERTENSIVE AGENT NOVO NORDISK A/S (DK) 2004-10-21 WO claimed
WO-2004089470-A2 NEW AMIDE DERIVATIVES AND PHARMACEUTICAL USE THEREOF NOVO NORDISK A/S (DK) 2004-10-21 WO claimed
WO-2004089415-A2 COMBINATIONS OF AN 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITOR AND A GLUCOCORTICOID RECEPTOR AGONIST NOVO NORDISK A/S (DK) 2004-10-21 WO claimed
WO-2004045647-A1 AMPLIFICATION OF BIOTIN-MEDIATED TARGETING ACCESS PHARMACEUTICALS AUSTRALIA PTY LTD (AU) 2004-06-03 WO claimed
US-6635782-B2 Using microorganism in culture media; polylactones; biodegradable, melt processability CANON KABUSHIKI KAISHA (JP) 2003-10-21 US claimed
US-20030100084-A1 Polyhydroxyalkanoate containing 3-hydroxybenzoylalkanoic acid as monomer unit, and method for producing the same CANON KABUSHIKI KAISHA (JP) 2003-05-29 US claimed
US-20020160467-A1 Polyhydroxyalkanoate and manufacturing method thereof CANON KABUSHIKI KAISHA (JP) 2002-10-31 US claimed
EP-1188782-A2 Polyhydroxyalkanoate and manufacturing method thereof CANON KABUSHIKI KAISHA (JP) 2002-03-20 EP claimed
EP-1130042-A2 Polyhydroxyalkanoate containing 3-hydroxybenzoylalkanoic acid as monomer unit, and method for producing the same CANON KABUSHIKI KAISHA (JP) 2001-09-05 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260083866-A1 COMPOSITIONS TARGETING ENDOTHELIAL CELLS AND USES THEREOF FLT1, VCAM1, FLT4 HDAC1 4452/4885HDAC8 4327/4885HDAC3 4696/4885
US-20260069697-A1 METHOD OF TREATING CANCER PBK, GZMB, KLRK1 HDAC1 4560/4885HDAC8 2483/4885HDAC3 3370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.