Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL5038662 | 0.95 | NPSR1 (0.36) | NPSR1TP53MEN1LMNAAPEX1 | |
| SCHEMBL5692209 | 0.85 | TSHR (0.37) | — | |
| Sulfuric Acid SCHEMBL576878 | 0.83 | CA5A (0.40) | NPSR1TP53MEN1LMNAAPEX1 | |
| Sulfuric Acid SCHEMBL8079703 | 0.80 | CA5A (0.38) | NPSR1TP53MEN1LMNAAPEX1 | |
| Sulfuric Acid SCHEMBL78884 | 0.80 | NPSR1 (0.46) | NPSR1TP53MEN1APEX1BLM | |
| Sulfuric Acid SCHEMBL16059228 | 0.80 | NPSR1 (0.46) | NPSR1TP53MEN1APEX1BLM | |
| Sulfuric Acid SCHEMBL1334876 | 0.80 | NPSR1 (0.46) | NPSR1TP53MEN1APEX1BLM | |
| Sulfuric Acid SCHEMBL11137355 | 0.80 | NPSR1 (0.46) | NPSR1TP53MEN1APEX1BLM | |
| Sulfuric Acid SCHEMBL29289482 | 0.80 | NPSR1 (0.46) | NPSR1TP53MEN1APEX1BLM | |
| Sulfuric Acid SCHEMBL11137352 | 0.80 | NPSR1 (0.46) | NPSR1TP53MEN1APEX1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120309952-A1 | SMALL RNA PURIFICATION | PROMEGA CORPORATION (US) | 2012-12-06 | — | — | US | disclosed |
| EP-1996730-A2 | SMALL RNA PURIFICATION | PROMEGA CORPORATION (US) | 2008-12-03 | — | — | EP | disclosed |
| US-20070249821-A1 | Small RNA purification | PROMEGA CORPORATION (US) | 2007-10-25 | — | — | US | disclosed |
| WO-2007103485-A2 | SMALL RNA PURIFICATION | PROMEGA CORPORATION (US) | 2007-09-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249821-A1 | Small RNA purification | ZFR, EMG1, SNRPA1 | NPSR1 2732/4885TP53 2278/4885MEN1 1855/4885 |
| US-20120309952-A1 | SMALL RNA PURIFICATION | ZFR, EMG1, SNRPA1 | NPSR1 2732/4885TP53 2278/4885MEN1 1855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.