Sulfuric Acid

Sulfuric Acid

SCHEMBL8079703

CC(O)N(C(C)O)C(C)O.O.O=S(=O)(O)O

nearest known ligand 0.38

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA5A P35218 1/20 0.38
CA5B Q9Y2D0 1/20 0.38
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
POLB P06746 2/20 0.34
LMNA P02545 2/20 0.34
KMT2A Q03164 2/20 0.34
KDM4E B2RXH2 1/20 0.34
GMNN O75496 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
PMP22 Q01453 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
MEN1 O00255 1/20 0.31
APEX1 P27695 1/20 0.31
BLM P54132 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL576878 0.97 CA5A (0.40) CA5ACA5BCA1CA2POLB
SCHEMBL21924397 0.90 CA2 (0.37) CA5ACA5BCA1CA2POLB
Sulfuric Acid SCHEMBL11574272 0.88 CA5A (0.33) CA5ACA5BCA1CA2POLB
Thiosulfuric Acid SCHEMBL11126661 0.85 CA1 (0.33) CA1CA2POLB
Water SCHEMBL396554 0.83 ALDH1A1 (0.42) LMNAALDH1A1TDP1
SCHEMBL3018307 0.80 CA14 (0.34) CA1CA2
Sulfuric Acid SCHEMBL5033128 0.80 NPSR1 (0.36) LMNAKMT2ANPSR1MEN1APEX1
Tetradecane SCHEMBL98195 0.80 TP53 (0.52) CA1CA2KMT2AMEN1TP53
Sulfuric Acid SCHEMBL5038662 0.80 NPSR1 (0.36) LMNAKMT2ANPSR1MEN1APEX1
SCHEMBL37338 0.79 ALDH1A1 (0.46) LMNAALDH1A1TDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115043761-A Production method of alkyl sulfate triethanolamine salt product 湖南丽臣奥威实业有限公司 2022-09-13 CN disclosed
US-6028046-A WASHING DYED FABRIC WITH CLEANING COMPOUND COMPRISING POLYAMINE ALKOXYLATE WITCO CORPORATION (US) 2000-02-22 US disclosed
EP-0897972-A1 Detergents with polyamine alkoxylates useful in cleaning dyed fabrics while inhibiting dye transfer WITCO CORPORATION (US) 1999-02-24 EP disclosed
US-4744977-A ANIONIC SULFATE SURFACTANTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1988-05-17 US disclosed
EP-0264977-A1 Detergency builders and built detergents THE PROCTER & GAMBLE COMPANY (US) 1988-04-27 EP disclosed