Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 2/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.35 |
| ▸ | MAP3K6 | O95382 | 1/20 | 0.35 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.35 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CDK7 | P50613 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2192291 | 0.77 | SLC2A1 (0.48) | CDK2SLC2A1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL30535675 | 0.76 | RXFP1 (0.47) | CDK2SLC2A1ALDH1A1KDM4ERXFP1 | |
| SCHEMBL5033485 | 0.76 | SLC2A1 (0.41) | SLC2A1ALDH1A1KDM4EPTGS2SMN1; SMN2 | |
| SCHEMBL4385774 | 0.76 | SMN1; SMN2 (0.37) | SLC2A1ALDH1A1KDM4EPTGS2SMN1; SMN2 | |
| SCHEMBL31058752 | 0.76 | KDM4E (0.50) | CDK2ALDH1A1KDM4ERXFP1CTSA | |
| SCHEMBL10602621 | 0.73 | CDK2 (0.49) | CDK2SLC2A1ALDH1A1KDM4ERXFP1 | |
| SCHEMBL5048198 | 0.72 | CPA1 (0.51) | CDK2ALDH1A1KDM4ERXFP1CTSA | |
| SCHEMBL3578267 | 0.72 | ALDH1A1 (0.53) | CDK2ALDH1A1KDM4ERXFP1PTGS2 | |
| SCHEMBL8542833 | 0.72 | CDK2 (0.62) | CDK2SLC2A1ALDH1A1KDM4ERXFP1 | |
| SCHEMBL2640836 | 0.71 | ALDH1A1 (0.53) | CDK2ALDH1A1KDM4ERXFP1MAP3K7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080233127-A1 | IMIDAZOLOPYRIMIDINE ANALOGS AND THEIR USE AS PI3 KINASE AND MTOR INHIBITORS | WYETH (US) | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080233127-A1 | IMIDAZOLOPYRIMIDINE ANALOGS AND THEIR USE AS PI3 KINASE AND MTOR INHIBITORS | MTOR, RICTOR, MTMR1 | CDK2 306/4885SLC2A1 618/4885ALDH1A1 3278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.