SCHEMBL31058752

SCHEMBL31058752

CC(O)c1ncc2[nH]cnc2n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.50
ALDH1A1 P00352 1/20 0.50
RXFP1 Q9HBX9 1/20 0.44
CDK2 P24941 3/20 0.41
PAK1 Q13153 1/20 0.39
APLNR P35414 1/20 0.36
POLA1 P09884 1/20 0.36
MAP3K7 O43318 1/20 0.35
MAP3K6 O95382 1/20 0.35
MAP3K5 Q99683 1/20 0.35
CDK1 P06493 2/20 0.35
CCNB1 P14635 2/20 0.35
CCNT1 O60563 1/20 0.35
CDK7 P50613 1/20 0.35
CDK9 P50750 1/20 0.35
CCNH P51946 1/20 0.35
SORD Q00796 3/20 0.32
TP53 P04637 1/20 0.31
CCNA2 P20248 1/20 0.31
CCNA1 P78396 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3578267 0.85 ALDH1A1 (0.53) KDM4EALDH1A1RXFP1CDK2PAK1
SCHEMBL2640836 0.83 ALDH1A1 (0.53) KDM4EALDH1A1RXFP1CDK2PAK1
SCHEMBL4447459 0.79 KDM4E (0.47) KDM4EALDH1A1RXFP1CDK2PAK1
SCHEMBL5033486 0.76 CDK2 (0.49) KDM4EALDH1A1RXFP1CDK2PAK1
SCHEMBL375956 0.75 ALDH1A1 (0.59) KDM4EALDH1A1RXFP1CDK2PAK1
SCHEMBL28839814 0.75 ALDH1A1 (0.46) KDM4EALDH1A1RXFP1CDK2PAK1
Isopropyl Alcohol SCHEMBL10551705 0.75 CDK2 (0.51) KDM4EALDH1A1RXFP1CDK2PAK1
SCHEMBL16178779 0.74 ALDH1A1 (0.46) KDM4EALDH1A1RXFP1CDK2PAK1
SCHEMBL8741748 0.73 KDM4E (0.49) KDM4EALDH1A1RXFP1CDK2PAK1
SCHEMBL7943075 0.73 KDM4E (0.41) KDM4EALDH1A1RXFP1CDK2PAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118652276-B Preparation process of compound for treating cancer diseases 成都工业学院 2024-10-15 CN disclosed
CN-118652276-A Preparation process of compound for treating cancer diseases 成都工业学院 2024-09-17 CN disclosed