SCHEMBL5033790

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5027387	0.91	IL2 (0.40)	IL2TNFSTIM1ORAI1HTT
	SCHEMBL8233603	0.87	IL2 (0.38)	IL2TNFSTIM1ORAI1MEN1
	SCHEMBL5029494	0.84	STIM1 (0.51)	IL2STIM1ORAI1HTTKMT2A
	SCHEMBL4764710	0.83	IL2 (0.58)	IL2TNFSTIM1ORAI1HTT
	SCHEMBL2891752	0.82	IL2 (0.46)	IL2TNFSTIM1ORAI1HTT
	SCHEMBL8228071	0.80	ADORA2A (0.41)	STIM1ORAI1TYK2MEN1KMT2A
	SCHEMBL8236360	0.80	LMNA (0.48)	ORAI1HTTMEN1KMT2AKDM4E
	SCHEMBL4767857	0.79	IL2 (0.61)	IL2HTTJAK2JAK1TYK2
	SCHEMBL15249596	0.79	IL2 (0.56)	IL2TNFSTIM1ORAI1HTT
	SCHEMBL2893143	0.78	IL2 (0.46)	IL2TNFSTIM1ORAI1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.