⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1767952 | 0.82 | HRH4 (0.41) | — | |
| Acetic Acid SCHEMBL27485830 | 0.81 | LOXL2 (0.32) | — | |
| SCHEMBL1325051 | 0.78 | — | — | |
| SCHEMBL28242957 | 0.76 | — | — | |
| SCHEMBL558512 | 0.76 | PRKCE (0.34) | — | |
| Dimethylamine SCHEMBL9053689 | 0.75 | HRH4 (0.45) | — | |
| SCHEMBL15891878 | 0.74 | KDM4E (0.31) | — | |
| SCHEMBL30871910 | 0.74 | KDM4E (0.31) | — | |
| SCHEMBL25659073 | 0.74 | ALDH1A1 (0.35) | — | |
| SCHEMBL805489 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118125982-A | Synthesis method of 5-fluoro-6-ethyl-4-hydroxypyrimidine | 风火轮(上海)生物科技有限公司 | 2024-06-04 | — | — | CN | claimed |
| EP-0326389-B1 | Process for preparing 4-hydroxypyrimidine | UBE INDUSTRIES (JP) | 1996-09-11 | — | — | EP | claimed |
| US-4935516-A | Process for preparing 4-hydroxypyrimidine | UBE INDUSTRIES, LTD. (JP) | 1990-06-19 | — | — | US | claimed |
| EP-0326389-A2 | Process for preparing 4-hydroxypyrimidine | UBE INDUSTRIES, LTD. (JP) | 1989-08-02 | — | — | EP | claimed |
| EP-4543890-A1 | USP1 INHIBITORS AND USES THEREOF | Forma Therapeutics, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| CN-119731178-A | USP1 inhibitors and uses thereof | 福马治疗有限公司 | 2025-03-28 | — | — | CN | disclosed |
| US-20240317725-A1 | LPA1 SMALL MOLECULE ANTAGONIST | TUOJIE BIOTECH (SHANGHAI) CO., LTD. (CN) | 2024-09-26 | — | — | US | disclosed |
| CN-118125982-A | Synthesis method of 5-fluoro-6-ethyl-4-hydroxypyrimidine | 风火轮(上海)生物科技有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-118125982-A | Synthesis method of 5-fluoro-6-ethyl-4-hydroxypyrimidine | 风火轮(上海)生物科技有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-117460721-A | LPA1 small molecule antagonist | 上海拓界生物医药科技有限公司 | 2024-01-26 | — | — | CN | disclosed |
| WO-2023250084-A1 | USP1 INHIBITORS AND USES THEREOF | FORMA THERAPEUTICS, INC. (US) | 2023-12-28 | — | — | WO | disclosed |
| WO-2023001177-A1 | LPA1 SMALL MOLECULE ANTAGONIST | 上海拓界生物医药科技有限公司 | 2023-01-26 | — | — | WO | disclosed |
| EP-0572259-A1 | Aminoquinolone derivatives as anti-HIV agents | UBE INDUSTRIES, LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |
| WO-1993022291-A1 | ARTHROPODICIDAL AND FUNGICIDAL AMINOPYRIMIDINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-11-11 | — | — | WO | disclosed |
| CN-1058776-A | Agricultural chemicals | CIBA GEIGY AG (CH) | 1992-02-19 | — | — | CN | disclosed |
| EP-0470600-A1 | Naphthylalkylaminopyrimidine derivatives, process for their preparation and pesticides containing them | CIBA-GEIGY AG (CH) | 1992-02-12 | — | — | EP | disclosed |
| US-4977264-A | Condensing 2-chloro-3-oxo-pentanoic acid ester with formamidinium salt, reacting with phosphoryl chloride | LONZA LTD. (CH) | 1990-12-11 | — | — | US | disclosed |
| US-4935516-A | Process for preparing 4-hydroxypyrimidine | UBE INDUSTRIES, LTD. (JP) | 1990-06-19 | — | — | US | disclosed |
| EP-0370391-A2 | Process for the preparation of 4,5-dichloro-6-ethyl pyrimidine | LONZA AG (CH) | 1990-05-30 | — | — | EP | disclosed |
| EP-0326389-A2 | Process for preparing 4-hydroxypyrimidine | UBE INDUSTRIES, LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |