Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LHCGR | P22888 | 16/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | FSHR | P23945 | 5/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5140326 | 0.92 | LHCGR (0.73) | LHCGRTSHRFSHRMEN1NPC1 | |
| SCHEMBL5038376 | 0.92 | LHCGR (0.75) | LHCGRTSHRFSHR | |
| SCHEMBL4429264 | 0.90 | LHCGR (0.52) | LHCGRTSHRFSHRHTR2A | |
| SCHEMBL5043515 | 0.84 | LHCGR (0.82) | LHCGRTSHRFSHR | |
| SCHEMBL14285232 | 0.84 | LHCGR (0.76) | LHCGRTSHRFSHRMEN1NPC1 | |
| SCHEMBL5034024 | 0.82 | LHCGR (0.65) | LHCGRTSHRFSHRMEN1NPC1 | |
| SCHEMBL4430406 | 0.82 | LHCGR (0.58) | LHCGRTSHRFSHR | |
| SCHEMBL32156160 | 0.81 | LHCGR (1.00) | LHCGRTSHRFSHRMEN1NPC1 | |
| SCHEMBL4326072 | 0.81 | LHCGR (1.00) | LHCGRTSHRFSHRMEN1NPC1 | |
| SCHEMBL4429897 | 0.81 | LHCGR (0.80) | LHCGRTSHRFSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1886999-A2 | Bicyclic heteroaromatic compound | N.V. Organon (NL) | 2008-02-13 | — | — | EP | disclosed |