SCHEMBL5034191

SCHEMBL5034191

COCc1cc(O)c2nc(C)c(C)n2c1

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.33
CYP2C9 P11712 4/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
PRKCG P05129 1/20 0.30
MAPT P10636 1/20 0.30
PRKCA P17252 1/20 0.30
APEX1 P27695 1/20 0.30
RECQL P46063 1/20 0.30
PRKCE Q02156 1/20 0.30
KMT2A Q03164 1/20 0.30
MYLK Q15746 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5034255 0.74 ATP4A (0.51) CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19
SCHEMBL27824101 0.72 ALDH1A1 (0.31) CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19
SCHEMBL6634689 0.71 CYP3A4 (0.60) CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19
Hydrochloric Acid SCHEMBL6354567 0.70 CYP3A4 (0.59) CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19
SCHEMBL4573822 0.70 CA12 (0.48) CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19
SCHEMBL5036927 0.66 CYP3A4 (0.35) CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19
Alcohol SCHEMBL4974198 0.65 CYP3A4 (0.38) CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19
SCHEMBL11785165 0.65 KDM4E (0.37) CYP3A4MEN1ALDH1A1PRKCGMAPT
SCHEMBL24614011 0.62 PRKCE (0.54) CYP3A4CYP2C9CYP1A2MEN1ALDH1A1
SCHEMBL4881228 0.62 CYP3A4 (0.61) CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7326718-B2 8-Substituted imidazopyridines ALTANA PHARMA AG (DE) 2008-02-05 US disclosed
US-20060100234-A1 8-Substituted imidazopyridines ALTANA PHARMA AG (DE) 2006-05-11 US disclosed
EP-1565465-A1 8-SUBSTITUTED IMIDAZOPYRIDINES ALTANA Pharma AG (DE) 2005-08-24 EP disclosed
WO-2004046144-A1 8-SUBSTITUTED IMIDAZOPYRIDINES ALTANA PHARMA AG (DE) 2004-06-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060100234-A1 8-Substituted imidazopyridines VIP, GIPR, SI CYP3A4 36/4885CYP2C9 153/4885CYP1A2 109/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.